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Polyglycolic Acid Felt Sealing Method for Prevention of Bleeding Related to Endoscopic Submucosal Dissection in Patients Taking Antithrombotic Agents
Joint Authors
Fukuda, Hiroko
Yamaguchi, Naoyuki
Isomoto, Hajime
Matsushima, Kayoko
Minami, Hitomi
Akazawa, Yuko
Ohnita, Ken
Shikuwa, Saburo
Takeshima, Fuminao
Nakao, Kazuhiko
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background and Study Aims.
When performing endoscopic submucosal dissection (ESD) for patients on antithrombotic agents, the frequency of delayed bleeding is expected to increase.
The endoscopic polyglycolic acid (PGA) felt and fibrin glue sealing method could be a new method for prevention of delayed bleeding.
Patients and Methods.
The safety and efficacy of the endoscopic tissue sealing method with PGA sheets and fibrin glue for the prevention of post-ESD bleeding were examined in 104 patients taking antithrombotic agents.
During the study period, 70 patients taking antithrombotic agents did not undergo the sealing method, 36 patients discontinued antithrombotic agents, and 724 patients had not received antithrombotic therapy.
Results.
Delayed bleeding rates were 3.8% (4/104) in the sealing group, 12.9% (9/70) in the nonsealing group, 8.3% (3/36) in the discontinuation group, and 4.6% (33/724) in the nonantithrombotic therapy group.
Thus, the delayed bleeding rate was significantly lower in the sealing group than in the nonsealing group and comparable to that in the nonantithrombotic therapy group.
Conclusions.
This PGA felt and fibrin glue sealing method might become a promising post-ESD bleeding prevention method in patients taking antithrombotic agents (UMIN000013990, UMIN000013993).
American Psychological Association (APA)
Fukuda, Hiroko& Yamaguchi, Naoyuki& Isomoto, Hajime& Matsushima, Kayoko& Minami, Hitomi& Akazawa, Yuko…[et al.]. 2016. Polyglycolic Acid Felt Sealing Method for Prevention of Bleeding Related to Endoscopic Submucosal Dissection in Patients Taking Antithrombotic Agents. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104589
Modern Language Association (MLA)
Fukuda, Hiroko…[et al.]. Polyglycolic Acid Felt Sealing Method for Prevention of Bleeding Related to Endoscopic Submucosal Dissection in Patients Taking Antithrombotic Agents. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1104589
American Medical Association (AMA)
Fukuda, Hiroko& Yamaguchi, Naoyuki& Isomoto, Hajime& Matsushima, Kayoko& Minami, Hitomi& Akazawa, Yuko…[et al.]. Polyglycolic Acid Felt Sealing Method for Prevention of Bleeding Related to Endoscopic Submucosal Dissection in Patients Taking Antithrombotic Agents. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104589
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104589