The Immunological Basis of Inflammatory Bowel Disease
Joint Authors
Ayrizono, Maria de Lourdes Setsuko
Silva, Francesca A. R.
Rodrigues, Bruno L.
Leal, Raquel F.
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Inflammatory bowel diseases (IBDs) are chronic ailments, Crohn’s disease and ulcerative colitis being the most important.
These diseases present an inflammatory profile and they differ according to pathophysiology, the affected area in the gastrointestinal tract, and the depth of the inflammation in the intestinal wall.
The immune characteristics of IBD arise from abnormal responses of the innate and adaptive immune system.
The number of Th17 cells increases in the peripheral blood of IBD patients, while Treg cells decrease, suggesting that the Th17/Treg proportion plays an important role in the development and maintenance of inflammation.
The purpose of this review was to determine the current state of knowledge on the immunological basis of IBD.
Many studies have shown the need for further explanation of the development and maintenance of the inflammatory process.
American Psychological Association (APA)
Silva, Francesca A. R.& Rodrigues, Bruno L.& Ayrizono, Maria de Lourdes Setsuko& Leal, Raquel F.. 2016. The Immunological Basis of Inflammatory Bowel Disease. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104610
Modern Language Association (MLA)
Silva, Francesca A. R.…[et al.]. The Immunological Basis of Inflammatory Bowel Disease. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1104610
American Medical Association (AMA)
Silva, Francesca A. R.& Rodrigues, Bruno L.& Ayrizono, Maria de Lourdes Setsuko& Leal, Raquel F.. The Immunological Basis of Inflammatory Bowel Disease. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104610
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104610