Postoperative Complications of Laparoscopic Total Gastrectomy versus Open Total Gastrectomy for Gastric Cancer in a Meta-Analysis of High-Quality Case-Controlled Studies
Joint Authors
Inokuchi, Mikito
Otsuki, Sho
Kojima, Kazuyuki
Ogawa, Norihito
Tanioka, Toshiro
Okuno, Keisuke
Gokita, Kentaro
Kawano, Tatsuyuki
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
Some meta-analyses of case-controlled studies (CCSs) have shown that laparoscopic or laparoscopy-assisted total gastrectomy (LTG) had some short-term advantages over open total gastrectomy (OTG).
However, postoperative complications differed somewhat among the meta-analyses, and some CCSs included in the meta-analyses had mismatched factors between LTG and OTG.
Methods.
CCSs comparing postoperative complications between LTG and OTG were identified in PubMed and Embase.
Studies matched for patients’ status, tumor stage, and the extents of lymph-node dissection were included.
Outcomes of interest, such as anastomotic, other intra-abdominal, wound, and pulmonary complications, were evaluated in a meta-analysis performed using Review Manager version 5.3 software.
Result.
This meta-analysis included a total of 2,560 patients (LTG, 1,073 patients; OTG, 1,487 patients) from 15 CCSs.
Wound complications were significantly less frequent in LTG than in OTG (n = 2,430; odds ratio [OR] 0.30, 95% confidence interval [CI] 0.29–0.85, P=0.01, I2 = 0%, and OR 0.46, 95% CI 0.17–0.52, P<0.0001, I2 = 0%).
However, the incidence of anastomotic complications was slightly but not significantly higher in LTG than in OTG (n = 2,560; OR 1.44, 95% CI 0.96–2.16, P=0.08, I2 = 0%).
Conclusion.
LTG was associated with a lower incidence of wound-related postoperative complications than was OTG in this meta-analysis of CCSs; however, some concern remains about anastomotic problems associated with LTG.
American Psychological Association (APA)
Inokuchi, Mikito& Otsuki, Sho& Ogawa, Norihito& Tanioka, Toshiro& Okuno, Keisuke& Gokita, Kentaro…[et al.]. 2016. Postoperative Complications of Laparoscopic Total Gastrectomy versus Open Total Gastrectomy for Gastric Cancer in a Meta-Analysis of High-Quality Case-Controlled Studies. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1104627
Modern Language Association (MLA)
Inokuchi, Mikito…[et al.]. Postoperative Complications of Laparoscopic Total Gastrectomy versus Open Total Gastrectomy for Gastric Cancer in a Meta-Analysis of High-Quality Case-Controlled Studies. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1104627
American Medical Association (AMA)
Inokuchi, Mikito& Otsuki, Sho& Ogawa, Norihito& Tanioka, Toshiro& Okuno, Keisuke& Gokita, Kentaro…[et al.]. Postoperative Complications of Laparoscopic Total Gastrectomy versus Open Total Gastrectomy for Gastric Cancer in a Meta-Analysis of High-Quality Case-Controlled Studies. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1104627
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104627