Esophageal Endoscopic Submucosal Dissection Assisted by an Overtube with a Traction Forceps: An Animal Study
Joint Authors
Sakai, Eiji
Nonaka, Kouichi
Fu, Kuangi
Ohno, Akiko
Ito, Takafumi
Tsuji, Yosuke
Chiba, Hideyuki
Yamawaki, Makoto
Hemmi, Hideyuki
Nakaya, Teruo
Fukushima, Junichi
Minato, Yohei
Tashima, Tomoaki
Ohata, Ken
Matsuhashi, Nobuyuki
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Esophageal endoscopic submucosal dissection (ESD) is technically difficult.
To make it safer, we developed a novel method using overtube with a traction forceps (OTF) for countertraction during submucosal dissection.
We conducted an ex vivo animal study and compared the clinical outcomes between OTF-ESD and conventional method (C-ESD).
A total of 32 esophageal ESD procedures were performed by four beginner and expert endoscopists.
After circumferential mucosal incision for the target lesion, structured as the isolated pig esophagus 3 cm long, either C-ESD or OTF-ESD was randomly selected for submucosal dissection.
All the ESD procedures were completed as en bloc resections, while perforation only occurred in a beginner’s C-ESD procedure.
The dissection time for OTF-ESD was significantly shorter than that for C-ESD for both the beginner and expert endoscopists ( 22.8 ± 8.3 min versus 7.8 ± 4.5 min, P < 0.001 , and 11.3 ± 4.4 min versus 5.9 ± 2.5 min, P = 0.01 , resp.).
The frequency and volume of the submucosal injections were significantly smaller for OTF-ESD than for C-ESD ( 1.3 ± 0.6 times versus 2.9 ± 1.5 times, P < 0.001 , and 5.3 ± 2.8 mL versus 15.6 ± 7.3 mL, P < 0.001 , resp.).
Histologically, muscular injury was more common among the C-ESD procedures (80% versus 13%, P = 0.009 ).
Our results indicated that the OTF-ESD technique is useful for the safe and easy completion of esophageal ESD.
American Psychological Association (APA)
Ohata, Ken& Fu, Kuangi& Sakai, Eiji& Nonaka, Kouichi& Tashima, Tomoaki& Minato, Yohei…[et al.]. 2016. Esophageal Endoscopic Submucosal Dissection Assisted by an Overtube with a Traction Forceps: An Animal Study. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104652
Modern Language Association (MLA)
Ohata, Ken…[et al.]. Esophageal Endoscopic Submucosal Dissection Assisted by an Overtube with a Traction Forceps: An Animal Study. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1104652
American Medical Association (AMA)
Ohata, Ken& Fu, Kuangi& Sakai, Eiji& Nonaka, Kouichi& Tashima, Tomoaki& Minato, Yohei…[et al.]. Esophageal Endoscopic Submucosal Dissection Assisted by an Overtube with a Traction Forceps: An Animal Study. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104652
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104652