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Elevated Preoperative Neutrophil-Lymphocyte Ratio Is Associated with Poor Prognosis in Hepatocellular Carcinoma Patients Treated with Liver Transplantation: A Meta-Analysis
Joint Authors
Sun, Xiao-Dong
Shi, Xiao-Ju
Wang, Chuan-Lei
Lv, Guo-Yue
Chen, Yu-Guo
Ma, Qiang
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
This study aims to investigate the prognostic value of neutrophil to lymphocyte ratio (NLR) in hepatocellular carcinoma (HCC) patients treated with liver transplantation (LT) through meta-analysis.
Relevant articles were sought in PubMed, Embase, and Wangfang databases up to July 2015.
A total of 1687 patients from 10 studies were included in this meta-analysis.
Meta-analysis results showed that elevated NLR was significantly associated with poorer overall survival (OS) (HR = 2.71, 95% CI: 1.91–3.83) and poorer disease-free survival (DFS) (HR = 3.61, 95% CI: 2.23–5.84) in HCC patients treated with LT.
Moreover, subgroup analysis showed the significant association between elevated preoperative NLR and poor prognosis was not altered by cutoff values of NLR or types of LT.
Therefore, elevated preoperative NLR is associated with poor prognosis in HCC patients treated with LT.
Preoperative NLR should be used to predict the prognosis of HCC after LT in our clinical work.
American Psychological Association (APA)
Sun, Xiao-Dong& Shi, Xiao-Ju& Chen, Yu-Guo& Wang, Chuan-Lei& Ma, Qiang& Lv, Guo-Yue. 2015. Elevated Preoperative Neutrophil-Lymphocyte Ratio Is Associated with Poor Prognosis in Hepatocellular Carcinoma Patients Treated with Liver Transplantation: A Meta-Analysis. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1104695
Modern Language Association (MLA)
Sun, Xiao-Dong…[et al.]. Elevated Preoperative Neutrophil-Lymphocyte Ratio Is Associated with Poor Prognosis in Hepatocellular Carcinoma Patients Treated with Liver Transplantation: A Meta-Analysis. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1104695
American Medical Association (AMA)
Sun, Xiao-Dong& Shi, Xiao-Ju& Chen, Yu-Guo& Wang, Chuan-Lei& Ma, Qiang& Lv, Guo-Yue. Elevated Preoperative Neutrophil-Lymphocyte Ratio Is Associated with Poor Prognosis in Hepatocellular Carcinoma Patients Treated with Liver Transplantation: A Meta-Analysis. Gastroenterology Research and Practice. 2015. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1104695
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104695