Preoperative Nutritional Therapy Reduces the Risk of Anastomotic Leakage in Patients with Crohn’s Disease Requiring Resections
Joint Authors
Guo, Zhen
Guo, Dong
Gong, Jianfeng
Zhu, Weiming
Zuo, Lugen
Sun, Jing
Li, Ning
Li, Jieshou
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The rate of anastomotic leakage is high in surgeries for Crohn’s disease, and therefore a temporary diverting stoma is often needed.
We conducted this study to investigate whether preoperative nutritional therapy could reduce the risk of anastomotic leakage while decreasing the frequency of temporary stoma formation.
Methods.
This was a retrospective study.
Patients requiring bowel resections due to Crohn’s disease were reviewed.
The rate of anastomotic leakage and temporary diverting stoma was compared between patients who received preoperative nutritional therapy and those on a normal diet before surgery.
Possible predictive factors for anastomotic leakage were also analyzed.
Results.
One hundred and fourteen patients undergoing 123 surgeries were included.
Patients in nutritional therapy (NT) group had a significantly lower level of C-reactive protein on the day before surgery.
Patients in NT group suffered less anastomotic leakage (2.3% versus 17.9%, P=0.023) and less temporary diverting stoma (22.8% versus 40.9%, P=0.036).
Serum albumin of the day before surgery ≤35 g/L and preoperative nutritional therapy were identified as factors which independently affected the rate of anastomotic leakage.
Conclusion.
Preoperative nutritional therapy reduced the risk of anastomotic leakage and the frequency of temporary diverting stoma formation in patients with Crohn’s disease requiring resections.
American Psychological Association (APA)
Guo, Zhen& Guo, Dong& Gong, Jianfeng& Zhu, Weiming& Zuo, Lugen& Sun, Jing…[et al.]. 2015. Preoperative Nutritional Therapy Reduces the Risk of Anastomotic Leakage in Patients with Crohn’s Disease Requiring Resections. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104699
Modern Language Association (MLA)
Guo, Zhen…[et al.]. Preoperative Nutritional Therapy Reduces the Risk of Anastomotic Leakage in Patients with Crohn’s Disease Requiring Resections. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1104699
American Medical Association (AMA)
Guo, Zhen& Guo, Dong& Gong, Jianfeng& Zhu, Weiming& Zuo, Lugen& Sun, Jing…[et al.]. Preoperative Nutritional Therapy Reduces the Risk of Anastomotic Leakage in Patients with Crohn’s Disease Requiring Resections. Gastroenterology Research and Practice. 2015. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104699
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104699