Clinical Outcome of Eradication Therapy for Gastric Mucosa-Associated Lymphoid Tissue Lymphoma according to H. pylori Infection Status
Joint Authors
Moon, Hee Seok
Kang, Sun Hyung
Sung, Jae Kyu
Jeong, Hyun Yong
Kim, Ju Seok
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
To evaluate the long-term outcome of H.
pylori eradication therapy for gastric MALT lymphoma according to the presence of H.
pylori infection.
Methods.
We retrospectively reviewed the medical records of patients between January 2001 and June 2014.
The clinicopathologic characteristics and clinical outcomes were compared between H.
pylori-positive and H.
pylori-negative gastric MALT lymphoma groups.
Results.
Fifty-four patients were enrolled: 12 H.
pylori-negative and 42 H.
pylori-positive patients.
The tumor was located more frequently in both the proximal and distal parts of the stomach ( P = 0 .
001 ), and the percentage of multiple lesions was significantly greater in the H.
pylori-negative group ( P = 0 .
046 ).
Forty-seven patients received initial eradication therapy, and 85% (35/41) of H.
pylori-positive patients and 50% (3/6) of H.
pylori-negative patients achieved complete remission after eradication therapy.
The presence of multiple lesions was a predictive factor for unresponsiveness to H.
pylori eradication ( P = 0 .
02 4 ).
The efficacy of eradication therapy ( P = 0 .
133 ), complete remission (CR) maintenance period, and relapse after eradication therapy were not significantly different between the two groups.
Conclusions.
H.
pylori eradication therapy could be an effective first-line treatment for localized H.
pylori-negative gastric MALT lymphoma, especially for single lesions.
American Psychological Association (APA)
Kim, Ju Seok& Kang, Sun Hyung& Moon, Hee Seok& Sung, Jae Kyu& Jeong, Hyun Yong. 2016. Clinical Outcome of Eradication Therapy for Gastric Mucosa-Associated Lymphoid Tissue Lymphoma according to H. pylori Infection Status. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104755
Modern Language Association (MLA)
Kim, Ju Seok…[et al.]. Clinical Outcome of Eradication Therapy for Gastric Mucosa-Associated Lymphoid Tissue Lymphoma according to H. pylori Infection Status. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1104755
American Medical Association (AMA)
Kim, Ju Seok& Kang, Sun Hyung& Moon, Hee Seok& Sung, Jae Kyu& Jeong, Hyun Yong. Clinical Outcome of Eradication Therapy for Gastric Mucosa-Associated Lymphoid Tissue Lymphoma according to H. pylori Infection Status. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104755
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104755