Current Role of Minimally Invasive Radical Cholecystectomy for Gallbladder Cancer
Joint Authors
Ramera, Marco
Zimmitti, Giuseppe
Manzoni, Alberto
Guerini, Francesca
Aroldi, Francesca
Zaniboni, Alberto
Rosso, Edoardo
Bertocchi, Paola
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-03
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
For Tis and T1a gallbladder cancer (GbC), laparoscopic cholecystectomy can provide similar survival outcomes compared to open cholecystectomy.
However, for patients affected by resectable T1b or more advanced GbC, open approach radical cholecystectomy (RC), consisting in gallbladder liver bed resection or segment 4b-5 bisegmentectomy, with locoregional lymphadenectomy, is considered the gold standard while minimally invasive RC (MiRC) is skeptically considered.
Aim.
To analyze current literature on perioperative and oncologic outcomes of MiRC for patients affected by GbC.
Methods.
A Medline review of published articles until June 2016 concerning MiRC for GbC was performed.
Results.
Data relevant for this review were presented in 13 articles, including 152 patients undergoing an attempt of MiRC for GbC.
No randomized clinical trial was found.
The approach was laparoscopic in 147 patients and robotic in five.
Conversion was required in 15 (10%) patients.
Postoperative complications rate was 10% with no mortality.
Long-term survival outcomes were reported by 11 studies, two of them showing similar oncologic results when comparing MiRC with matched open RC.
Conclusions.
Although randomized clinical trials are still lacking and only descriptive studies reporting on limited number of patients are available, current literature seems suggesting that when performed at highly specialized centers, MiRC for GbC is safe and feasible and has oncologic outcomes comparable to open RC.
American Psychological Association (APA)
Zimmitti, Giuseppe& Manzoni, Alberto& Guerini, Francesca& Ramera, Marco& Bertocchi, Paola& Aroldi, Francesca…[et al.]. 2016. Current Role of Minimally Invasive Radical Cholecystectomy for Gallbladder Cancer. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104788
Modern Language Association (MLA)
Zimmitti, Giuseppe…[et al.]. Current Role of Minimally Invasive Radical Cholecystectomy for Gallbladder Cancer. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1104788
American Medical Association (AMA)
Zimmitti, Giuseppe& Manzoni, Alberto& Guerini, Francesca& Ramera, Marco& Bertocchi, Paola& Aroldi, Francesca…[et al.]. Current Role of Minimally Invasive Radical Cholecystectomy for Gallbladder Cancer. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104788
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104788