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Diagnostic Value of Fecal Calprotectin (S100 A8A9) Test in Children with Chronic Abdominal Pain
Joint Authors
Pieczarkowski, Stanisław
Kowalska-Duplaga, Kinga
Tomasik, Przemysław
Wędrychowicz, Andrzej
Fyderek, Krzysztof
Kwinta, Przemko
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-15
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objectives.
The aim of the study was to establish whether fecal calprotectin concentration (FCC) may be useful in children with chronic abdominal pain to differentiate between inflammatory bowel disease (IBD), other inflammatory gastrointestinal disorders, and functional gastrointestinal disorders.
Methods.
The study included 163 patients (median age 13 years), who were assigned to four study groups: group 0 (control), 22 healthy children; group 1, 33 children with functional gastrointestinal disorders; group 2, 71 children with inflammatory gastrointestinal disorders other than IBD; group 3, 37 children with IBD.
FCC was measured using ELISA assay.
Results.
In group 0 and group 1 FCCs were below 100 μg/g.
Low FCCs were found in 91% of patients in group 2.
In patients with IBD FCCs were markedly elevated with median value of 1191.5 μg/g.
However, in children with inflammatory gastrointestinal disorders other than IBD and in children with IBD mean FCCs were significantly higher compared with the control group.
Significant differences in FCCs were also found between group 1 and group 2, between group 1 and group 3, and between group 2 and group 3.
Conclusion.
FCC is the best parameter allowing for differentiation between IBD, other inflammatory gastrointestinal disorders, and functional gastrointestinal disorders.
High FCC is associated with a high probability of IBD and/or other inflammatory gastrointestinal disorders, and it allows excluding functional gastrointestinal disorders.
American Psychological Association (APA)
Pieczarkowski, Stanisław& Kowalska-Duplaga, Kinga& Kwinta, Przemko& Tomasik, Przemysław& Wędrychowicz, Andrzej& Fyderek, Krzysztof. 2016. Diagnostic Value of Fecal Calprotectin (S100 A8A9) Test in Children with Chronic Abdominal Pain. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104799
Modern Language Association (MLA)
Pieczarkowski, Stanisław…[et al.]. Diagnostic Value of Fecal Calprotectin (S100 A8A9) Test in Children with Chronic Abdominal Pain. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1104799
American Medical Association (AMA)
Pieczarkowski, Stanisław& Kowalska-Duplaga, Kinga& Kwinta, Przemko& Tomasik, Przemysław& Wędrychowicz, Andrzej& Fyderek, Krzysztof. Diagnostic Value of Fecal Calprotectin (S100 A8A9) Test in Children with Chronic Abdominal Pain. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104799
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104799