Distinct Clinic-Pathological Features of Early Differentiated-Type Gastric Cancers after Helicobacter pylori Eradication
Joint Authors
Horiguchi, Noriyuki
Tahara, Tomomitsu
Kawamura, Tomohiko
Okubo, Masaaki
Ishizuka, Takamitsu
Nakagawa, Yoshihito
Nagasaka, Mitsuo
Shibata, T.
Ohmiya, Naoki
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Gastric cancer is discovered even after successful eradication of H.
pylori.
We investigated clinic pathological features of early gastric cancers after H.
pylori eradication.
Methods.
51 early gastric cancers (EGCs) from 44 patients diagnosed after successful H.
pylori eradication were included as eradication group.
The clinic-pathological features were compared with that of 131 EGCs from 120 patients who did not have a history of H.
pylori eradication (control group).
Results.
Compared with control group, clinic-pathological features of eradication group were characterized as depressed ( p < 0.0001 ), reddish ( p = 0.0001 ), and smaller ( p = 0.0095 ) lesions, which was also confirmed in the comparison of six metachronous lesions diagnosed after initial ESD and subsequent successful H.
pylori eradication.
Prevalence of both SM2 (submucosal invasion greater than 500 μm) and unexpected SM2 cases tended to be higher in eradication group ( p = 0.077 , 0.0867, resp.).
Prevalence of inconclusive diagnosis of gastric cancer during pretreatment biopsy was also higher in the same group (26.0% versus 1.6%, p < 0.0001 ).
Conclusions.
Informative clinic pathological features of EGC after H.
pylori eradication are depressed, reddish appearances, which should be treated as a caution because histological diagnosis of cancerous tissue is sometimes difficult by endoscopic biopsy.
American Psychological Association (APA)
Horiguchi, Noriyuki& Tahara, Tomomitsu& Kawamura, Tomohiko& Okubo, Masaaki& Ishizuka, Takamitsu& Nakagawa, Yoshihito…[et al.]. 2016. Distinct Clinic-Pathological Features of Early Differentiated-Type Gastric Cancers after Helicobacter pylori Eradication. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1104802
Modern Language Association (MLA)
Horiguchi, Noriyuki…[et al.]. Distinct Clinic-Pathological Features of Early Differentiated-Type Gastric Cancers after Helicobacter pylori Eradication. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1104802
American Medical Association (AMA)
Horiguchi, Noriyuki& Tahara, Tomomitsu& Kawamura, Tomohiko& Okubo, Masaaki& Ishizuka, Takamitsu& Nakagawa, Yoshihito…[et al.]. Distinct Clinic-Pathological Features of Early Differentiated-Type Gastric Cancers after Helicobacter pylori Eradication. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1104802
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104802