Quantitative Analysis of Intestinal Flora of Uygur and Han Ethnic Chinese Patients with Ulcerative Colitis
Joint Authors
Yao, Ping
Cui, Min
Wang, Haikun
Gao, Hongliang
Wang, Lei
Yang, Tao
Cheng, Yongbo
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Aim.
To study the correlation between intestinal flora and ulcerative colitis by analyzing the abundance of Bacteroides, Fusobacterium, Clostridium, Bifidobacterium spp., and Faecalibacterium prausnitzii in the intestinal of ulcerative colitis (UC) patients and healthy controls with Uygur and Han ethnic.
Methods.
Bacterial genomic DNA was extracted from fecal samples and analyzed with real-time fluorescence quantitative polymerase chain reaction (PCR) to identify the abundance of Bacteroides, Fusobacterium, Clostridium, Bifidobacterium spp., and Faecalibacterium prausnitzii.
Results.
The samples from UC patients, Uygur and Han ethnic combined, had higher abundance of Bacteroides ( P = 0.026 ) but lower Clostridium ( P = 0.004 ), Bifidobacterium spp.
( P = 0.009 ), and Faecalibacterium prausnitzii ( P = 0.008 ) than those from healthy controls.
Among UC patients, Bacteroides population was raised in acute UC patients ( P ≤ 0.05 ), while the abundance of Clostridium, Bifidobacterium spp., Fusobacterium, and Faecalibacterium prausnitzii decreased ( P ≤ 0.05 ) compared with the remission.
In both UC patients group and control group, no difference was observed in the abundance of these 5 bacteria between the Han and the Uygur group.
Conclusions.
Variations in the abundance of these five bacterial strains in intestines may be associated with the occurrence of UC in Uygur and Han populations; however, these variations were not associated with ethnic difference.
American Psychological Association (APA)
Yao, Ping& Cui, Min& Wang, Haikun& Gao, Hongliang& Wang, Lei& Yang, Tao…[et al.]. 2015. Quantitative Analysis of Intestinal Flora of Uygur and Han Ethnic Chinese Patients with Ulcerative Colitis. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104829
Modern Language Association (MLA)
Yao, Ping…[et al.]. Quantitative Analysis of Intestinal Flora of Uygur and Han Ethnic Chinese Patients with Ulcerative Colitis. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1104829
American Medical Association (AMA)
Yao, Ping& Cui, Min& Wang, Haikun& Gao, Hongliang& Wang, Lei& Yang, Tao…[et al.]. Quantitative Analysis of Intestinal Flora of Uygur and Han Ethnic Chinese Patients with Ulcerative Colitis. Gastroenterology Research and Practice. 2015. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104829
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104829