Gastrointestinal Symptoms of Patients with Fabry Disease
Joint Authors
Strisciuglio, P.
Concolino, Daniela
Sestito, Simona
Pensabene, Licia
Nicoletti, Angela
Graziano, Francesca
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
In order to characterize gastrointestinal (GI) symptoms of 50 patients with Fabry disease (FD) (22 M; age range: 4–70 y; 35 adults and 15 children), validated questionnaires of GI symptoms were used to diagnose the functional gastrointestinal disorders (FGIDs) of the patients with GI symptoms (33/50 (66%); 25/35 adults and 8/15 children) according to Rome III criteria.
In 16/25 of these adults and 2/8 of these children, the symptoms mimicked FGID.
The adult subgroup included patients with unspecified functional bowel disorder ( n = 9 ), functional bloating ( n = 7 ), and IBS ( n = 5 ), and the child subgroup included patients with abdominal migraine ( n = 1 ) and IBS ( n = 1 ).
Among the 25 adults, 14 reported feeling full after a regular-size meal, and 12 complained of abdominal bloating/distension.
All of the children with GI symptoms complained of low abdominal pain associated with changes in the form of the stool/improvements with defecation.
In conclusion, according to Rome III criteria, the most frequent diagnoses of FGID among the adults with FD were unspecified functional bowel disorder, followed by functional bloating and IBS.
The most frequent GI symptom in the children in our population was IBS-like abdominal pain, while the adults exhibited a full feeling following a regular-size meal and abdominal bloating/distension.
American Psychological Association (APA)
Pensabene, Licia& Sestito, Simona& Nicoletti, Angela& Graziano, Francesca& Strisciuglio, P.& Concolino, Daniela. 2015. Gastrointestinal Symptoms of Patients with Fabry Disease. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104854
Modern Language Association (MLA)
Pensabene, Licia…[et al.]. Gastrointestinal Symptoms of Patients with Fabry Disease. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1104854
American Medical Association (AMA)
Pensabene, Licia& Sestito, Simona& Nicoletti, Angela& Graziano, Francesca& Strisciuglio, P.& Concolino, Daniela. Gastrointestinal Symptoms of Patients with Fabry Disease. Gastroenterology Research and Practice. 2015. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104854
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104854