The Emerging Role of miRNAs and Their Clinical Implication in Biliary Tract Cancer
Joint Authors
Calcagno, Danielle Queiroz
Burbano, Rommel Rodríguez
Ferreira Martins, Nina Nayara
da Silva Oliveira, Kelly Cristina
Braga Bona, Amanda
Arruda Cardoso Smith, Marília de
Ishak, Geraldo
Assumpção, Paulo Pimentel
Source
Gastroenterology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-27
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Biliary tract cancers are aggressive malignancies that include gallbladder cancer and tumors of intra- and extrahepatic ducts and have a poor prognosis.
Surgical resection remains the main curative therapy.
Nevertheless, numerous patients experience recurrence even after radical surgery.
This scenario drives the research to identify biliary tract cancer biomarkers despite the limited progress that has been made.
Recently, a large number of studies have demonstrated that deregulated expression of microRNAs is closely associated with cancer development and progression.
In this review, we highlight the role and importance of microRNAs in biliary tract cancers with an emphasis on utilizing circulating microRNAs as potential biomarkers.
Additionally, we report several single-nucleotide polymorphisms in microRNA genes that are associated with the susceptibility of biliary tract tumors.
American Psychological Association (APA)
Ferreira Martins, Nina Nayara& da Silva Oliveira, Kelly Cristina& Braga Bona, Amanda& Arruda Cardoso Smith, Marília de& Ishak, Geraldo& Assumpção, Paulo Pimentel…[et al.]. 2016. The Emerging Role of miRNAs and Their Clinical Implication in Biliary Tract Cancer. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1104858
Modern Language Association (MLA)
Ferreira Martins, Nina Nayara…[et al.]. The Emerging Role of miRNAs and Their Clinical Implication in Biliary Tract Cancer. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1104858
American Medical Association (AMA)
Ferreira Martins, Nina Nayara& da Silva Oliveira, Kelly Cristina& Braga Bona, Amanda& Arruda Cardoso Smith, Marília de& Ishak, Geraldo& Assumpção, Paulo Pimentel…[et al.]. The Emerging Role of miRNAs and Their Clinical Implication in Biliary Tract Cancer. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1104858
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104858