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Sol-Gel Derived Mg-Based Ceramic Scaffolds Doped with Zinc or Copper Ions: Preliminary Results on Their Synthesis, Characterization, and Biocompatibility
Joint Authors
Paraskevopoulos, Konstantinos M.
Bakopoulou, Athina
Theodorou, Georgios S.
Kontonasaki, Eleana
Theocharidou, Anna
Bousnaki, Maria
Hadjichristou, Christina
Papachristou, Eleni
Papadopoulou, Lambrini
Kantiranis, Nikolaos A.
Chrissafis, Konstantinos
Koidis, Petros T.
Source
International Journal of Biomaterials
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Glass-ceramic scaffolds containing Mg have shown recently the potential to enhance the proliferation, differentiation, and biomineralization of stem cells in vitro, property that makes them promising candidates for dental tissue regeneration.
An additional property of a scaffold aimed at dental tissue regeneration is to protect the regeneration process against oral bacteria penetration.
In this respect, novel bioactive scaffolds containing Mg2+ and Cu2+ or Zn2+, ions known for their antimicrobial properties, were synthesized by the foam replica technique and tested regarding their bioactive response in SBF, mechanical properties, degradation, and porosity.
Finally their ability to support the attachment and long-term proliferation of Dental Pulp Stem Cells (DPSCs) was also evaluated.
The results showed that conversely to their bioactive response in SBF solution, Zn-doped scaffolds proved to respond adequately regarding their mechanical strength and to be efficient regarding their biological response, in comparison to Cu-doped scaffolds, which makes them promising candidates for targeted dental stem cell odontogenic differentiation and calcified dental tissue engineering.
American Psychological Association (APA)
Theodorou, Georgios S.& Kontonasaki, Eleana& Theocharidou, Anna& Bakopoulou, Athina& Bousnaki, Maria& Hadjichristou, Christina…[et al.]. 2016. Sol-Gel Derived Mg-Based Ceramic Scaffolds Doped with Zinc or Copper Ions: Preliminary Results on Their Synthesis, Characterization, and Biocompatibility. International Journal of Biomaterials،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1105460
Modern Language Association (MLA)
Theodorou, Georgios S.…[et al.]. Sol-Gel Derived Mg-Based Ceramic Scaffolds Doped with Zinc or Copper Ions: Preliminary Results on Their Synthesis, Characterization, and Biocompatibility. International Journal of Biomaterials No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1105460
American Medical Association (AMA)
Theodorou, Georgios S.& Kontonasaki, Eleana& Theocharidou, Anna& Bakopoulou, Athina& Bousnaki, Maria& Hadjichristou, Christina…[et al.]. Sol-Gel Derived Mg-Based Ceramic Scaffolds Doped with Zinc or Copper Ions: Preliminary Results on Their Synthesis, Characterization, and Biocompatibility. International Journal of Biomaterials. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1105460
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1105460