New Biofunctional Loading of Natural Antimicrobial Agent in Biodegradable Polymeric Films for Biomedical Applications
Joint Authors
Mir, Mariam
Ali, Murtaza Najabat
Ansari, Umar
Ghafoor, Bakhtawar
Bhatti, Muhammad Faraz
Akhtar, Hafsah
Darakhshan, Fatima
Source
International Journal of Biomaterials
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-14
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The study focuses on the development of novel Aloe vera based polymeric composite films and antimicrobial suture coatings.
Polyvinyl alcohol (PVA), a synthetic biocompatible and biodegradable polymer, was combined with Aloe vera, a natural herb used for soothing burning effects and cosmetic purposes.
The properties of these two materials were combined together to get additional benefits such as wound healing and prevention of surgical site infections.
PVA and Aloe vera were mixed in a fixed quantity to produce polymer based films.
The films were screened for antibacterial and antifungal activity against bacterial (E.
coli, P.
aeruginosa) and fungal strains (Aspergillus flavus and Aspergillus tubingensis) screened.
Aloe vera based PVA films showed antimicrobial activity against all the strains; the lowest Aloe vera concentration (5%) showed the highest activity against all the strains.
In vitro degradation and release profile of these films was also evaluated.
The coating for sutures was prepared, in vitro antibacterial tests of these coated sutures were carried out, and later on in vivo studies of these coated sutures were also performed.
The results showed that sutures coated with Aloe vera/PVA coating solution have antibacterial effects and thus have the potential to be used in the prevention of surgical site infections and Aloe vera/PVA based films have the potential to be used for wound healing purposes.
American Psychological Association (APA)
Ghafoor, Bakhtawar& Ali, Murtaza Najabat& Ansari, Umar& Bhatti, Muhammad Faraz& Mir, Mariam& Akhtar, Hafsah…[et al.]. 2016. New Biofunctional Loading of Natural Antimicrobial Agent in Biodegradable Polymeric Films for Biomedical Applications. International Journal of Biomaterials،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1105466
Modern Language Association (MLA)
Ghafoor, Bakhtawar…[et al.]. New Biofunctional Loading of Natural Antimicrobial Agent in Biodegradable Polymeric Films for Biomedical Applications. International Journal of Biomaterials No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1105466
American Medical Association (AMA)
Ghafoor, Bakhtawar& Ali, Murtaza Najabat& Ansari, Umar& Bhatti, Muhammad Faraz& Mir, Mariam& Akhtar, Hafsah…[et al.]. New Biofunctional Loading of Natural Antimicrobial Agent in Biodegradable Polymeric Films for Biomedical Applications. International Journal of Biomaterials. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1105466
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1105466