Changes in Testosterone Levels and Sex Hormone-Binding Globulin Levels in Extremely Obese Men after Bariatric Surgery
Joint Authors
Boonchaya-anant, Patchaya
Laichuthai, Nitchakarn
Suwannasrisuk, Preaw
Houngngam, Natnicha
Udomsawaengsup, Suthep
Snabboon, Thiti
Source
International Journal of Endocrinology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-20
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
Obesity is a risk factor for hypogonadotropic hypogonadism in men.
Weight loss has been shown to improve hypogonadism in obese men.
This study evaluated the early changes in sex hormones profile after bariatric surgery.
Methods.
This is a prospective study including 29 morbidly obese men.
Main outcomes were changes in serum levels of total testosterone (TT), free testosterone (cFT), SHBG, estradiol, adiponectin, and leptin at 1 and 6 months after surgery.
Results.
The mean age of patients was 31 ± 8 years and the mean BMI was 56.8 ± 11.7 kg/m2.
Fifteen patients underwent Roux-en-Y gastric bypass and 14 patients underwent sleeve gastrectomy.
At baseline, 22 patients (75.9%) had either low TT levels (<10.4 nmol/L) or low cFT levels (<225 pmol/L).
Total testosterone and SHBG levels increased significantly at 1 month after surgery ( p ≤ 0.001 ).
At 6 months after surgery, TT and cFT increased significantly ( p ≤ 0.001 ) and 22 patients (75.9%) had normalized TT and cFT levels.
There were no changes in estradiol levels at either 1 month or 6 months after surgery.
Conclusions.
Increases in TT and SHBG levels occurred early at 1 month after bariatric surgery while improvements in cFT levels were observed at 6 months after bariatric surgery.
American Psychological Association (APA)
Boonchaya-anant, Patchaya& Laichuthai, Nitchakarn& Suwannasrisuk, Preaw& Houngngam, Natnicha& Udomsawaengsup, Suthep& Snabboon, Thiti. 2016. Changes in Testosterone Levels and Sex Hormone-Binding Globulin Levels in Extremely Obese Men after Bariatric Surgery. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1105756
Modern Language Association (MLA)
Boonchaya-anant, Patchaya…[et al.]. Changes in Testosterone Levels and Sex Hormone-Binding Globulin Levels in Extremely Obese Men after Bariatric Surgery. International Journal of Endocrinology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1105756
American Medical Association (AMA)
Boonchaya-anant, Patchaya& Laichuthai, Nitchakarn& Suwannasrisuk, Preaw& Houngngam, Natnicha& Udomsawaengsup, Suthep& Snabboon, Thiti. Changes in Testosterone Levels and Sex Hormone-Binding Globulin Levels in Extremely Obese Men after Bariatric Surgery. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1105756
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1105756