A Study on Central Lymph Node Metastasis in 543 cN0 Papillary Thyroid Carcinoma Patients
Joint Authors
Yan, Huanhuan
Zhou, Xiaoqian
Jin, Hui
Li, Xiang
Zheng, Miao
Ming, Xu
Wang, Ruitao
Liu, Jun
Source
International Journal of Endocrinology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-03
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Papillary thyroid carcinoma (PTC) with central lymph node metastases (CLNMs) is common.
The objective of this study was to investigate the incidence and risk factors of lymph node metastasis patients with PTC.
Patients and Methods.
Between January 2013 and February 2015, a retrospective study of 543 patients with PTC undergoing hemithyroidectomy or total thyroidectomy with routine central lymph node dissection (CLND) was analyzed.
Clinicopathologic risk factors for CLNM were studied using univariate and multivariate analysis by SPSS 22.0 software.
Results.
The incidence of CLNMs in PTC patients was 38.1% (207/543).
In the multivariate analysis, male gender (p<0.001, OR: 1.984), age <45 years (p<0.001, OR: 1.934), bilaterality (p=0.006, OR: 1.585), tumor size ≥0.25 cm (p=0.001, OR: 7.655), and external extension (p=0.001, OR: 7.579) were independent risk factors of CLNMs.
Furthermore, in PTC patients with tumor size <0.25 cm, all 7 males and 21 patients with unilaterality were not found to have CLNMs.
Conclusions.
CLNMs are prevalent in the PTC patients with the following risk factors: male gender, age <45 years, bilaterality, tumor size ≥0.25 cm, and external extension.
PTC patients with tumor size <0.25 cm, male patients, and patients with unilateral lesion could be considered safe from CLNMs.
American Psychological Association (APA)
Yan, Huanhuan& Zhou, Xiaoqian& Jin, Hui& Li, Xiang& Zheng, Miao& Ming, Xu…[et al.]. 2016. A Study on Central Lymph Node Metastasis in 543 cN0 Papillary Thyroid Carcinoma Patients. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1105799
Modern Language Association (MLA)
Yan, Huanhuan…[et al.]. A Study on Central Lymph Node Metastasis in 543 cN0 Papillary Thyroid Carcinoma Patients. International Journal of Endocrinology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1105799
American Medical Association (AMA)
Yan, Huanhuan& Zhou, Xiaoqian& Jin, Hui& Li, Xiang& Zheng, Miao& Ming, Xu…[et al.]. A Study on Central Lymph Node Metastasis in 543 cN0 Papillary Thyroid Carcinoma Patients. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1105799
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1105799