Abnormalities of Thyroid Hormone Metabolism during Systemic Illness: The Low T3 Syndrome in Different Clinical Settings
Joint Authors
Zantut-Wittmann, Denise E.
Moura Neto, Arnaldo
Source
International Journal of Endocrinology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Thyroid hormone abnormalities are common in critically ill patients.
For over three decades, a mild form of these abnormalities has been described in patients with several diseases under outpatient care.
These alterations in thyroid hormone economy are a part of the nonthyroidal illness and keep an important relationship with prognosis in most cases.
The main feature of this syndrome is a fall in free triiodothyronine (T3) levels with normal thyrotropin (TSH).
Free thyroxin (T4) and reverse T3 levels vary according to the underlying disease.
The importance of recognizing this condition in such patients is evident to physicians practicing in a variety of specialties, especially general medicine, to avoid misdiagnosing the much more common primary thyroid dysfunctions and indicating treatments that are often not beneficial.
This review focuses on the most common chronic diseases already known to present with alterations in serum thyroid hormone levels.
A short review of the common pathophysiology of the nonthyroidal illness is followed by the clinical and laboratorial presentation in each condition.
Finally, a clinical case vignette and a brief summary on the evidence about treatment of the nonthyroidal illness and on the future research topics to be addressed are presented.
American Psychological Association (APA)
Moura Neto, Arnaldo& Zantut-Wittmann, Denise E.. 2016. Abnormalities of Thyroid Hormone Metabolism during Systemic Illness: The Low T3 Syndrome in Different Clinical Settings. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1105807
Modern Language Association (MLA)
Moura Neto, Arnaldo& Zantut-Wittmann, Denise E.. Abnormalities of Thyroid Hormone Metabolism during Systemic Illness: The Low T3 Syndrome in Different Clinical Settings. International Journal of Endocrinology No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1105807
American Medical Association (AMA)
Moura Neto, Arnaldo& Zantut-Wittmann, Denise E.. Abnormalities of Thyroid Hormone Metabolism during Systemic Illness: The Low T3 Syndrome in Different Clinical Settings. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1105807
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1105807