Myoinositol and D-Chiro Inositol in Improving Insulin Resistance in Obese Male Children: Preliminary Data
Joint Authors
Mancini, Mario
Andreassi, Alice
Salvioni, Michela
Pelliccione, Fiore
Mantellassi, Gianna
Banderali, Giuseppe
Source
International Journal of Endocrinology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-01
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Myoinositol and D-chiro inositol, which are inositol isomers, have been shown to possess insulin-mimetic properties and to improve insulin resistance, especially in women with polycystic ovary syndrome.
However, it has not been determined if this relationship exists also in children.
Based on these previous findings, we hypothesized that inositol could be effective in improving insulin sensitivity in children with insulin resistance.
To evaluate this hypothesis, we administered both inositol formulations before carrying out an oral glucose tolerance test (OGTT) in a group of obese insulin-resistant male children with high basal insulin levels and compared the values obtained with an OGTT previously conducted without inositol, in the same group, with unchanged BMI.
Our results confirm that myoinositol and D-chiro inositol acutely reduce insulin increase after glucose intake mainly in children with high basal insulin level.
American Psychological Association (APA)
Mancini, Mario& Andreassi, Alice& Salvioni, Michela& Pelliccione, Fiore& Mantellassi, Gianna& Banderali, Giuseppe. 2016. Myoinositol and D-Chiro Inositol in Improving Insulin Resistance in Obese Male Children: Preliminary Data. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1106040
Modern Language Association (MLA)
Mancini, Mario…[et al.]. Myoinositol and D-Chiro Inositol in Improving Insulin Resistance in Obese Male Children: Preliminary Data. International Journal of Endocrinology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1106040
American Medical Association (AMA)
Mancini, Mario& Andreassi, Alice& Salvioni, Michela& Pelliccione, Fiore& Mantellassi, Gianna& Banderali, Giuseppe. Myoinositol and D-Chiro Inositol in Improving Insulin Resistance in Obese Male Children: Preliminary Data. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1106040
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106040