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A Quantitative Genomic Approach for Analysis of Fitness and Stress Related Traits in a Drosophila melanogaster Model Population
Joint Authors
Duun Rohde, Palle
Krag, Kristian
Loeschcke, Volker
Overgaard, Johannes
Sørensen, Peter
Nygaard Kristensen, Torsten
Source
International Journal of Genomics
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-19
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The ability of natural populations to withstand environmental stresses relies partly on their adaptive ability.
In this study, we used a subset of the Drosophila Genetic Reference Panel, a population of inbred, genome-sequenced lines derived from a natural population of Drosophila melanogaster, to investigate whether this population harbors genetic variation for a set of stress resistance and life history traits.
Using a genomic approach, we found substantial genetic variation for metabolic rate, heat stress resistance, expression of a major heat shock protein, and egg-to-adult viability investigated at a benign and a higher stressful temperature.
This suggests that these traits will be able to evolve.
In addition, we outline an approach to conduct pathway associations based on genomic linear models, which has potential to identify adaptive genes and pathways, and therefore can be a valuable tool in conservation genomics.
American Psychological Association (APA)
Duun Rohde, Palle& Krag, Kristian& Loeschcke, Volker& Overgaard, Johannes& Sørensen, Peter& Nygaard Kristensen, Torsten. 2016. A Quantitative Genomic Approach for Analysis of Fitness and Stress Related Traits in a Drosophila melanogaster Model Population. International Journal of Genomics،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1106144
Modern Language Association (MLA)
Duun Rohde, Palle…[et al.]. A Quantitative Genomic Approach for Analysis of Fitness and Stress Related Traits in a Drosophila melanogaster Model Population. International Journal of Genomics No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1106144
American Medical Association (AMA)
Duun Rohde, Palle& Krag, Kristian& Loeschcke, Volker& Overgaard, Johannes& Sørensen, Peter& Nygaard Kristensen, Torsten. A Quantitative Genomic Approach for Analysis of Fitness and Stress Related Traits in a Drosophila melanogaster Model Population. International Journal of Genomics. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1106144
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106144