Differential Methylation of Genomic Regions Associated with Heteroblasty Detected by M&M Algorithm in the Nonmodel Species Eucalyptus globulus Labill.
Joint Authors
Hasbún, Rodrigo
Iturra, Carolina
Bravo, Soraya
Rebolledo-Jaramillo, Boris
Valledor, Luis
Source
International Journal of Genomics
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Epigenetic regulation plays important biological roles in plants, including timing of flowering and endosperm development.
Little is known about the mechanisms controlling heterochrony (the change in the timing or rate of developmental events during ontogeny) in Eucalyptus globulus.
DNA methylation has been proposed as a potential heterochrony regulatory mechanism in model species, but its role during the vegetative phase in E.
globulus has not been explored.
In order to investigate the molecular mechanisms governing heterochrony in E.
globulus, we have developed a workflow aimed at generating high-resolution hypermethylome and hypomethylome maps that have been tested in two stages of vegetative growth phase: juvenile (6-month leaves) and adult (30-month leaves).
We used the M&M algorithm, a computational approach that integrates MeDIP-seq and MRE-seq data, to identify differentially methylated regions (DMRs).
Thousands of DMRs between juvenile and adult leaves of E.
globulus were found.
Although further investigations are required to define the loci associated with heterochrony/heteroblasty that are regulated by DNA methylation, these results suggest that locus-specific methylation could be major regulators of vegetative phase change.
This information can support future conservation programs, for example, selecting the best methylomes for a determinate environment in a restoration project.
American Psychological Association (APA)
Hasbún, Rodrigo& Iturra, Carolina& Bravo, Soraya& Rebolledo-Jaramillo, Boris& Valledor, Luis. 2016. Differential Methylation of Genomic Regions Associated with Heteroblasty Detected by M&M Algorithm in the Nonmodel Species Eucalyptus globulus Labill.. International Journal of Genomics،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1106159
Modern Language Association (MLA)
Hasbún, Rodrigo…[et al.]. Differential Methylation of Genomic Regions Associated with Heteroblasty Detected by M&M Algorithm in the Nonmodel Species Eucalyptus globulus Labill.. International Journal of Genomics No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1106159
American Medical Association (AMA)
Hasbún, Rodrigo& Iturra, Carolina& Bravo, Soraya& Rebolledo-Jaramillo, Boris& Valledor, Luis. Differential Methylation of Genomic Regions Associated with Heteroblasty Detected by M&M Algorithm in the Nonmodel Species Eucalyptus globulus Labill.. International Journal of Genomics. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1106159
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106159