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ElbasvirGrazoprevir: A Review of the Latest Agent in the Fight against Hepatitis C
Joint Authors
Bell, Allison M.
Wagner, Jamie L.
Barber, Katie E.
Stover, Kayla R.
Source
International Journal of Hepatology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Hepatitis C virus (HCV) is estimated to affect up to 150 million people worldwide.
Despite worldwide prevalence, treatment modalities prior to 2011 remained suboptimal, with low virologic response rates and intolerable side effect profiles.
Fortunately, the landscape of treatment for chronic hepatitis C has rapidly evolved since the introduction of HCV NS3/4 protease inhibitors in 2011.
Elbasvir, a NS5A inhibitor, combined with grazoprevir, a NS3/4A protease inhibitor, is the latest FDA-approved therapy for patients with genotype 1 or 4 chronic hepatitis C, with or without compensated cirrhosis.
This review will focus on the current literature and clinical evidence supporting elbasvir/grazoprevir as first-line therapy in patients with genotypes 1 and 4 chronic hepatitis C.
American Psychological Association (APA)
Bell, Allison M.& Wagner, Jamie L.& Barber, Katie E.& Stover, Kayla R.. 2016. ElbasvirGrazoprevir: A Review of the Latest Agent in the Fight against Hepatitis C. International Journal of Hepatology،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1106213
Modern Language Association (MLA)
Bell, Allison M.…[et al.]. ElbasvirGrazoprevir: A Review of the Latest Agent in the Fight against Hepatitis C. International Journal of Hepatology No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1106213
American Medical Association (AMA)
Bell, Allison M.& Wagner, Jamie L.& Barber, Katie E.& Stover, Kayla R.. ElbasvirGrazoprevir: A Review of the Latest Agent in the Fight against Hepatitis C. International Journal of Hepatology. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1106213
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106213