![](/images/graphics-bg.png)
The Hypertension of Hemophilia Is Not Explained by the Usual Cardiovascular Risk Factors: Results of a Cohort Study
Joint Authors
Barnes, Richard F. W.
Cramer, Thomas J.
Sait, Afrah S.
Kruse-Jarres, Rebecca
Quon, Doris V. K.
von Drygalski, A.
Source
International Journal of Hypertension
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-14
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Background.
The etiology of the high prevalence of hypertension among patients with hemophilia (PWH) remains unknown.
Methods.
We compared 469 PWH in the United States with males from the National Health and Nutrition Examination Survey (NHANES) to determine whether differences in cardiovascular risk factors can account for the hypertension in hemophilia.
Results.
Median systolic and diastolic BP were higher in PWH than NHANES (P<0.001) for subjects not taking antihypertensives.
Those taking antihypertensives showed similar differences.
Differences in both systolic and diastolic BP were especially marked among adults <30 years old.
Differences between PWH and NHANES persisted after adjusting for age and risk factors (body mass index, renal function, cholesterol, smoking, diabetes, Hepatitis C, and race).
Conclusions.
Systolic and diastolic BP are higher in PWH than in the general male population and especially among PWH < 30 years old.
The usual cardiovascular risk factors do not account for the etiology of the higher prevalence of hypertension in hemophilia.
New investigations into the missing link between hemophilia and hypertension should include age of onset of hypertension and hemophilia-specific morbidities such as the role of inflammatory joint disease.
American Psychological Association (APA)
Barnes, Richard F. W.& Cramer, Thomas J.& Sait, Afrah S.& Kruse-Jarres, Rebecca& Quon, Doris V. K.& von Drygalski, A.. 2016. The Hypertension of Hemophilia Is Not Explained by the Usual Cardiovascular Risk Factors: Results of a Cohort Study. International Journal of Hypertension،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1106227
Modern Language Association (MLA)
Barnes, Richard F. W.…[et al.]. The Hypertension of Hemophilia Is Not Explained by the Usual Cardiovascular Risk Factors: Results of a Cohort Study. International Journal of Hypertension No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1106227
American Medical Association (AMA)
Barnes, Richard F. W.& Cramer, Thomas J.& Sait, Afrah S.& Kruse-Jarres, Rebecca& Quon, Doris V. K.& von Drygalski, A.. The Hypertension of Hemophilia Is Not Explained by the Usual Cardiovascular Risk Factors: Results of a Cohort Study. International Journal of Hypertension. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1106227
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106227