The Association between ESR and CRP and Systemic Hypertension in Sarcoidosis
Joint Authors
Ebrahimi, Golnaz
Mirsaeidi, Mehdi
Omar, Hesham R.
Campos, Micheal
Source
International Journal of Hypertension
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Introduction.
The association between the level of systemic inflammation and systemic hypertension (sHTN) among subjects with sarcoidosis has not been previously explored.
Methods.
A retrospective study was conducted to investigate the relation between the level of systemic inflammation in sarcoidosis, measured by various serum inflammatory markers, and sHTN.
Results.
Among a total of 108 cases with sarcoidosis (mean age: 53.4 years, 76.9% females), 55 (50.9%) had sHTN and 53 (49.1%) were normotensive.
ESR was highly associated with sHTN.
The patients with sHTN had higher mean ESR levels compared with normotensives (48.8 ± 35 versus 23.2 ± 27 mm/hr, resp.; P = 0.001 ).
ROC curve analysis for ESR revealed an AUC value of 0.795 (95% CI: 0.692–0.897; P = 0.0001 ).
With regard to CRP, there was a trend towards higher mean values in sHTN group (3.4 versus 1.7 mg/L; P = 0.067 ) and significantly higher prevalence of sHTN in the highest CRP quartile compared to the lowest one (69.6% versus 30%; OR 4.95; P = 0.017 ).
ROC curve analysis for CRP revealed an AUC value of 0.644 (95% CI: 0.518–0.769; P = 0.03 ).
On multivariate analysis, ESR and the CRP remained independent predictors for sHTN among subjects with sarcoidosis.
Conclusion.
Systemic inflammation is associated with the presence of sHTN in sarcoidosis.
American Psychological Association (APA)
Mirsaeidi, Mehdi& Omar, Hesham R.& Ebrahimi, Golnaz& Campos, Micheal. 2016. The Association between ESR and CRP and Systemic Hypertension in Sarcoidosis. International Journal of Hypertension،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1106228
Modern Language Association (MLA)
Mirsaeidi, Mehdi…[et al.]. The Association between ESR and CRP and Systemic Hypertension in Sarcoidosis. International Journal of Hypertension No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1106228
American Medical Association (AMA)
Mirsaeidi, Mehdi& Omar, Hesham R.& Ebrahimi, Golnaz& Campos, Micheal. The Association between ESR and CRP and Systemic Hypertension in Sarcoidosis. International Journal of Hypertension. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1106228
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106228