Changes in Blood Pressure Levels and Antihypertensive Medication Use before and after Renal Transplantation among Patients in Nairobi, Kenya: A Comparative Cross-Sectional Study
Joint Authors
Kubo, Mary N.
Kayima, Joshua K.
McLigeyo, Seth O.
Ogola, Elijah N.
Were, Anthony J.
Ezzi, Mohammed S.
Source
International Journal of Hypertension
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-07
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objectives.
To determine the changes in blood pressure levels and antihypertensive medication use in the postrenal transplantation period compared to pretransplantation one.
Methods.
A comparative cross-sectional study was carried out on renal transplant recipients at the Kenyatta National Hospital, a national referral hospital in Kenya.
Sociodemographic details, blood pressure levels, and antihypertensive medication use before and after renal transplantation were noted.
Changes in mean blood pressure levels and mean number of antihypertensive medications after renal transplantation were determined using paired t-test.
Results.
85 subjects were evaluated.
Mean age was 42.4 (SD ± 12.2) years, with a male : female ratio of 1.9 : 1.
Compared to the pretransplant period, significantly lower mean systolic and diastolic blood pressure levels after transplantation were noted (mean SBP 144.5 mmHg versus 131.8 mmHg; mean DBP 103.6 mmHg versus 83.5 mmHg in the pre- and posttransplant periods, respectively, p<0.001).
Mean number of antihypertensive medications also reduced significantly after transplantation, with an average of 3.3 (±1.6) versus 2.1 (±0.9) in the pre- and posttransplant periods, respectively (p<0.001).
Conclusion.
There is a significant reduction in blood pressure levels and number of antihypertensive medications used after renal transplantation.
The positive impact of renal transplantation on blood pressure control should be confirmed using prospective cohort studies of patients with end stage renal disease who then undergo renal transplantation.
American Psychological Association (APA)
Kubo, Mary N.& Kayima, Joshua K.& Were, Anthony J.& Ezzi, Mohammed S.& McLigeyo, Seth O.& Ogola, Elijah N.. 2016. Changes in Blood Pressure Levels and Antihypertensive Medication Use before and after Renal Transplantation among Patients in Nairobi, Kenya: A Comparative Cross-Sectional Study. International Journal of Hypertension،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1106243
Modern Language Association (MLA)
Kubo, Mary N.…[et al.]. Changes in Blood Pressure Levels and Antihypertensive Medication Use before and after Renal Transplantation among Patients in Nairobi, Kenya: A Comparative Cross-Sectional Study. International Journal of Hypertension No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1106243
American Medical Association (AMA)
Kubo, Mary N.& Kayima, Joshua K.& Were, Anthony J.& Ezzi, Mohammed S.& McLigeyo, Seth O.& Ogola, Elijah N.. Changes in Blood Pressure Levels and Antihypertensive Medication Use before and after Renal Transplantation among Patients in Nairobi, Kenya: A Comparative Cross-Sectional Study. International Journal of Hypertension. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1106243
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106243