Intravenous Immunoglobulins: Mode of Action and Indications in Autoimmune and Inflammatory Dermatoses
Joint Authors
Guleva, Dimitrina V.
Dourmishev, Lyubomir
Miteva, Ljubka
Source
International Journal of Inflammation
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Intravenous immunoglobulins (IVIGs), a mixture of variable amounts of proteins (albumin, IgG, IgM, IgA, and IgE antibodies), as well as salt, sugar, solvents, and detergents, are successfully used to treat a variety of dermatological disorders.
For decades, IVIGs have been administered for treatment of infectious diseases and immune deficiencies, since they contain natural antibodies that represent a first-line defense against pathogens.
Today their indication has expanded, including the off-label therapy for a variety of autoimmune and inflammatory diseases.
In dermatology, IVIGs are administered for treatment of different disorders at different therapeutic regimens, mostly with higher doses then those administered for treatment of infectious diseases.
The aim of this prospective review is to highlight the indications, effectiveness, side effects, and perspectives of the systemic treatment with IVIGs for patients with severe, life-threatening, and resistant to conventional therapies autoimmune or inflammatory dermatoses.
American Psychological Association (APA)
Dourmishev, Lyubomir& Guleva, Dimitrina V.& Miteva, Ljubka. 2016. Intravenous Immunoglobulins: Mode of Action and Indications in Autoimmune and Inflammatory Dermatoses. International Journal of Inflammation،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106247
Modern Language Association (MLA)
Dourmishev, Lyubomir…[et al.]. Intravenous Immunoglobulins: Mode of Action and Indications in Autoimmune and Inflammatory Dermatoses. International Journal of Inflammation No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1106247
American Medical Association (AMA)
Dourmishev, Lyubomir& Guleva, Dimitrina V.& Miteva, Ljubka. Intravenous Immunoglobulins: Mode of Action and Indications in Autoimmune and Inflammatory Dermatoses. International Journal of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106247
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106247