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Audit of Helicobacter pylori Testing in Microbiology Laboratories in England: To Inform Compliance with NICE Guidance and the Feasibility of Routine Antimicrobial Resistance Surveillance
Joint Authors
Allison, Rosalie
Lecky, Donna M.
Bull, Megan
Turner, Kim
Godbole, Gauri
McNulty, Cliodna A. M.
Source
International Journal of Microbiology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
The National Institute for Health and Clinical Excellence (NICE) guidance recommends that dyspeptic patients are tested for Helicobacter pylori using a urea breath test, stool antigen test, or serology.
Antibiotic resistance in H.
pylori is globally increasing, but treatment in England is rarely guided by susceptibility testing or surveillance.
Aims.
To determine compliance of microbiology laboratories in England with NICE guidance and whether laboratories perform culture and antibiotic susceptibility testing (AST).
Methods.
In 2015, 170 accredited English microbiology laboratories were surveyed, by email.
Results.
121/170 (71%) laboratories responded; 96% provided H.
pylori testing (78% on site).
94% provided H.
pylori diagnosis using stool antigen; only four provided serology as their noninvasive test; 3/4 of these encouraged urea breath tests in their acute trusts.
Only 22/94 (23%) of the laboratories performed H.
pylori cultures from gastric biopsies on site; 9/22 performed AST, but the vast majority processed less than one specimen/week.
Conclusions.
Only five laboratories in England do not comply with NICE guidance; these will need the guidance reinforced.
National surveillance needs to be implemented; culture-based AST would need to be centralised.
Moving forward, detection of resistance in H.
pylori from stool specimens using molecular methods (PCR) needs to be explored.
American Psychological Association (APA)
Allison, Rosalie& Lecky, Donna M.& Bull, Megan& Turner, Kim& Godbole, Gauri& McNulty, Cliodna A. M.. 2016. Audit of Helicobacter pylori Testing in Microbiology Laboratories in England: To Inform Compliance with NICE Guidance and the Feasibility of Routine Antimicrobial Resistance Surveillance. International Journal of Microbiology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106290
Modern Language Association (MLA)
Allison, Rosalie…[et al.]. Audit of Helicobacter pylori Testing in Microbiology Laboratories in England: To Inform Compliance with NICE Guidance and the Feasibility of Routine Antimicrobial Resistance Surveillance. International Journal of Microbiology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1106290
American Medical Association (AMA)
Allison, Rosalie& Lecky, Donna M.& Bull, Megan& Turner, Kim& Godbole, Gauri& McNulty, Cliodna A. M.. Audit of Helicobacter pylori Testing in Microbiology Laboratories in England: To Inform Compliance with NICE Guidance and the Feasibility of Routine Antimicrobial Resistance Surveillance. International Journal of Microbiology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106290
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106290