Long-Term Follow-Up Evaluation of Renal Function in Patients with Chronic Kidney Disease Undergoing Cardiac Surgery

Abstract EN

Background.

Acute kidney injury (AKI) is a common complication of cardiac surgery but its long-term consequences, in patients with chronic kidney disease (CKD), are not known.

Methods.

We compared the long-term prognoses of CKD patients who developed ( n = 23 ) and did not develop ( n = 35 ) AKI during the period of hospitalization after undergoing coronary artery bypass graft (CABG).

Fifty-eight patients who survived ( 69.6 ± 8.4 years old, 72% males, 83% Whites, 52% diabetics, baseline GFR: 46 ± 16 mL/min) were followed up for 47.8 ± 16.4 months and treated for secondary prevention of events.

Results.

There were 6 deaths, 4 in the AKI+ and 2 in the AKI− group (Log-rank = 0.218), two attributed to CV causes.

At the end of the study, renal function was similar in the two groups.

One AKI− patient was started on dialysis.

Only 4 patients had an increase in serum creatinine ≥ 0.5 mg/dL during follow-up.

Conclusion.

CKD patients developing AKI that survived the early perioperative period of coronary intervention present good renal and nonrenal long-term prognosis, compared to patients who did not develop AKI.