Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Cinnamic Acid: Extraction of Cinnamic Acid from Spiked Blood Plasma
Joint Authors
Joke Chow, Alvin Leong
Bhawani, Showkat A.
Source
International Journal of Polymer Science
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-20
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The molecular imprinting technique is used to create the molecularly imprinted polymers (MIPs) with higher binding capacity towards the template.
In this research precipitation polymerization method with noncovalent approach was used to synthesize imprinted polymer microspheres.
The polymerization reaction was conducted in a flask containing acetonitrile as a porogen, cinnamic acid as a template (T), acrylic acid (AA) as a monomer, divinylbenzene (DVB) as a cross-linker, and azobisisobutyronitrile as an initiator.
The polymer particles were characterized by using SEM and FTIR.
The rebinding efficiency was conducted by batch binding assay and the results were monitored by using HPLC.
The batch binding results suggested MIP1 (T : AA : DVB, 1 : 6 : 20 molar ratio) is most suitable composition for the rebinding of cinnamic acid.
The highly selective polymer (MIP1) was used for the extraction of cinnamic acid from human plasma.
The extraction efficiency of imprinted polymer of cinnamic acid from spiked plasma was above 75%.
American Psychological Association (APA)
Joke Chow, Alvin Leong& Bhawani, Showkat A.. 2016. Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Cinnamic Acid: Extraction of Cinnamic Acid from Spiked Blood Plasma. International Journal of Polymer Science،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1106654
Modern Language Association (MLA)
Joke Chow, Alvin Leong& Bhawani, Showkat A.. Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Cinnamic Acid: Extraction of Cinnamic Acid from Spiked Blood Plasma. International Journal of Polymer Science No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1106654
American Medical Association (AMA)
Joke Chow, Alvin Leong& Bhawani, Showkat A.. Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Cinnamic Acid: Extraction of Cinnamic Acid from Spiked Blood Plasma. International Journal of Polymer Science. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1106654
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106654