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Carotid Intima Media Thickness in Nondiabetic Hypertensive Nigerians: Role of Fasting and Postprandial Blood Glucose
Joint Authors
Muoneme, S. A.
Kolade-Yunusa, H. O.
Okeahialam, Basil N.
Source
International Journal of Vascular Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-10
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background/Aims.
Carotid intima media thickness (CIMT) tracks atherosclerotic vascular disease.
Hypertension and diabetes chiefly contribute to atherosclerosis with 75% of symptomatic cardiovascular disease cases having dysglycaemia even in normal cases.
Hypothesising that postprandial hyperglycaemia contributes to cardiovascular morbidity, we sought to determine if any relationship existed between glycaemic profile in nondiabetic hypertensives and atherosclerosis.
Methods.
In a study of CIMT in nondiabetic, statin-naïve hypertensives, we evaluated fasting blood glucose (FBG) and 2-hour postprandial sugar (2hPPBG) in the patients and compared them with the CIMT.
CIMT was measured on both sides, 1 cm proximal to the carotid bulb using a 7.5 mHz transducer of ALOKA SSD-3500 ultrasound machine.
Results.
The subjects with complete data were 86 (63 F).
The mean (SD) of CIMT was 0.89 (0.15) mm, FBG 4.8 (0.097) mmol/L, and 2hPPBG 6.5 (1.81) mmol/L.
There was no significant correlation between FBG and 2hPPBG with CIMT.
Blood pressure had no bearing on this.
When blood glucose data were divided into quartiles and post hoc multiple comparison was done, there was significant difference in CIMT for the different ranges.
This was not so for 2hPPBG.
Conclusion.
Though expected from other studies, we did not show any significant correlation between FBG and 2hPPBG status and CIMT.
This may be our pattern as the degree of excursion of 2hPPBG was low.
There may be a threshold level above which PPBG starts to impact CIMT.
American Psychological Association (APA)
Okeahialam, Basil N.& Muoneme, S. A.& Kolade-Yunusa, H. O.. 2016. Carotid Intima Media Thickness in Nondiabetic Hypertensive Nigerians: Role of Fasting and Postprandial Blood Glucose. International Journal of Vascular Medicine،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1107101
Modern Language Association (MLA)
Okeahialam, Basil N.…[et al.]. Carotid Intima Media Thickness in Nondiabetic Hypertensive Nigerians: Role of Fasting and Postprandial Blood Glucose. International Journal of Vascular Medicine No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1107101
American Medical Association (AMA)
Okeahialam, Basil N.& Muoneme, S. A.& Kolade-Yunusa, H. O.. Carotid Intima Media Thickness in Nondiabetic Hypertensive Nigerians: Role of Fasting and Postprandial Blood Glucose. International Journal of Vascular Medicine. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1107101
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107101