Predictors of Staphylococcus aureus Colonization and Results after Decolonization
Joint Authors
Malcolm, Tennison L.
Robinson, Le Don
Klika, Alison K.
Ramanathan, Deepak
Higuera, Carlos A.
Murray, Trevor G.
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Protocols for the screening and decolonization of Staphylococcus aureus prior to total joint arthroplasty (TJA) have become widely adopted.
The goals of this study were to determine: (1) whether implementation of a screening protocol followed by decolonization with mupirocin/vancomycin and chlorhexidine reduces the risk of revision compared with no screening protocol (i.e., chlorhexidine alone) and (2) whether clinical criteria could reliably predict colonization with MSSA and/or MRSA.
Electronic medical records of primary patients undergoing TJA that were screened ( n = 3 ,927) and were not screened ( n = 1 ,751) for Staphylococcus aureus at least 4 days prior to surgery, respectively, were retrospectively reviewed.
All patients received chlorhexidine body wipes preoperatively.
Patients carrying MSSA and MRSA were treated preoperatively with mupirocin and vancomycin, respectively, along with the standard preoperative antibiotics and chlorhexidine body wipes.
Screened patients were 50% less likely to require revision due to prosthetic joint infection compared to those not screened ( p = 0.04 ).
Multivariate regression models were poorly accurate in predicting colonization with MSSA (AUC = 0.58) and MRSA (AUC = 0.62).
These results support the routine screening and decolonization of S.
aureus prior to TJA.
American Psychological Association (APA)
Malcolm, Tennison L.& Robinson, Le Don& Klika, Alison K.& Ramanathan, Deepak& Higuera, Carlos A.& Murray, Trevor G.. 2016. Predictors of Staphylococcus aureus Colonization and Results after Decolonization. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107139
Modern Language Association (MLA)
Malcolm, Tennison L.…[et al.]. Predictors of Staphylococcus aureus Colonization and Results after Decolonization. Interdisciplinary Perspectives on Infectious Diseases No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1107139
American Medical Association (AMA)
Malcolm, Tennison L.& Robinson, Le Don& Klika, Alison K.& Ramanathan, Deepak& Higuera, Carlos A.& Murray, Trevor G.. Predictors of Staphylococcus aureus Colonization and Results after Decolonization. Interdisciplinary Perspectives on Infectious Diseases. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107139
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107139