Ulcerative Colitis and Its Association with Salmonella Species
Joint Authors
Singh, Tej Bali
Tripathi, Manish Kumar
Dixit, Vinod K.
Shukla, Sunit K.
Nath, Gopal
Jain, Ashok Kumar
Pratap, Chandra Bhan
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-20
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Ulcerative colitis (UC) is characterized by presence of ulcer in colon and bloody diarrhea.
The present study explores the possibility of association between Salmonella and ulcerative colitis.
The present study comprised 59 cases of UC, 28 of colon cancer (CC), 127 of irritable bowel syndrome (IBS), and 190 of healthy control.
The serological study was done by Widal and Indirect Haemagglutination Assay (IHA) for ViAb.
Nested PCR was performed targeting fliC, staA, and stkG gene for Typhi and Paratyphi A, respectively.
A total of 15.3% patients were positive for Salmonella “O” antigen among them 18.6% UC, 35.5% CC, 12.6% IBS, and 15.3% healthy control.
A total of 36.9% patients were positive for “H” antigen including 39.0%, 57.1%, and 67.7% UC, CC, and IBS, respectively.
About 1.73% show positive agglutination for AH antigen including 3.4%, 3.6%, and 1.6%, UC, CC, and IBS.
A total of 10.89% were positive for ViAb.
While 6.8% of UC, 10.7% of CC, 11.0% of IBS, and 12.1% of healthy subjects were positive for the antibody, the PCR positivity rates for Salmonella specific sequences were 79.7% in UC, 53.6% in CC, 66.1% in IBS, and 16.3% in healthy controls.
The present study suggested that higher prevalence of Salmonella might play important role in etiopathogenesis of UC, IBS, and CC.
American Psychological Association (APA)
Tripathi, Manish Kumar& Pratap, Chandra Bhan& Dixit, Vinod K.& Singh, Tej Bali& Shukla, Sunit K.& Jain, Ashok Kumar…[et al.]. 2016. Ulcerative Colitis and Its Association with Salmonella Species. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1107149
Modern Language Association (MLA)
Tripathi, Manish Kumar…[et al.]. Ulcerative Colitis and Its Association with Salmonella Species. Interdisciplinary Perspectives on Infectious Diseases No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1107149
American Medical Association (AMA)
Tripathi, Manish Kumar& Pratap, Chandra Bhan& Dixit, Vinod K.& Singh, Tej Bali& Shukla, Sunit K.& Jain, Ashok Kumar…[et al.]. Ulcerative Colitis and Its Association with Salmonella Species. Interdisciplinary Perspectives on Infectious Diseases. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1107149
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107149