Prevalence, Characteristics, and One-Year Follow-Up of Congenital Cytomegalovirus Infection in Isfahan City, Iran
Joint Authors
Karimian, Pegah
Yaghini, Omid
Nasr Azadani, Hossein
Mohammadizadeh, Majid
Arabzadeh, Seyed Ali Mohammad
Adibi, Atosa
Rahimi, Hamid
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Introduction.
Need of neonatal screening for Cytomegalovirus (CMV) infection is under debate, in part because of limited data on importance of the disease regarding the prevalence of congenital CMV (cCMV) infection and associated morbidity and mortality.
We aimed to evaluate the prevalence and prognosis of cCMV infection in Iran, where there is high maternal seroprevalence of CMV.
Methodology.
This prospective study was conducted in Isfahan city, Iran, from 2014 to 2016.
CMV was investigated in urine specimens by using the real-time polymerase chain reaction (RT-PCR) method.
CMV-infected infants were examined for clinical and laboratory findings attributed to CMV infection and followed up for one year.
Results.
Among 1617 studied neonates, eight (0.49%) were positive for CMV infection.
CMV-infected neonates were more likely to be preterm than noninfected ones (25% versus 4.5%, p=0.0508), and they had lower birth weight.
Three out of the eight CMV-infected neonates had transient symptoms at birth.
At follow-up, one case had mild hearing loss.
Most patients had impaired growth during the one-year follow-up.
Conclusions.
The primary object of this study was determination of prevalence of cCMV infection in Iran as a developing country, which was at the lower range compared with other such countries.
cCMV infection may result in short-term impairment in growth.
American Psychological Association (APA)
Karimian, Pegah& Yaghini, Omid& Nasr Azadani, Hossein& Mohammadizadeh, Majid& Arabzadeh, Seyed Ali Mohammad& Adibi, Atosa…[et al.]. 2016. Prevalence, Characteristics, and One-Year Follow-Up of Congenital Cytomegalovirus Infection in Isfahan City, Iran. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107154
Modern Language Association (MLA)
Karimian, Pegah…[et al.]. Prevalence, Characteristics, and One-Year Follow-Up of Congenital Cytomegalovirus Infection in Isfahan City, Iran. Interdisciplinary Perspectives on Infectious Diseases No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1107154
American Medical Association (AMA)
Karimian, Pegah& Yaghini, Omid& Nasr Azadani, Hossein& Mohammadizadeh, Majid& Arabzadeh, Seyed Ali Mohammad& Adibi, Atosa…[et al.]. Prevalence, Characteristics, and One-Year Follow-Up of Congenital Cytomegalovirus Infection in Isfahan City, Iran. Interdisciplinary Perspectives on Infectious Diseases. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107154
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107154