Qualitative and Quantitative Analysis of Volatile Components of Zhengtian Pills Using Gas Chromatography Mass Spectrometry and Ultra-High Performance Liquid Chromatography
Joint Authors
Liu, Cui-ting
Zhang, Min
Yan, Ping
Liu, Hai-chan
Liu, Xing-yun
Zhan, Ruo-ting
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Zhengtian pills (ZTPs) are traditional Chinese medicine (TCM) which have been commonly used to treat headaches.
Volatile components of ZTPs extracted by ethyl acetate with an ultrasonic method were analyzed by gas chromatography mass spectrometry (GC-MS).
Twenty-two components were identified, accounting for 78.884% of the total components of volatile oil.
The three main volatile components including protocatechuic acid, ferulic acid, and ligustilide were simultaneously determined using ultra-high performance liquid chromatography coupled with diode array detection (UHPLC-DAD).
Baseline separation was achieved on an XB-C18 column with linear gradient elution of methanol-0.2% acetic acid aqueous solution.
The UHPLC-DAD method provided good linearity ( R 2 ≥ 0.9992 ), precision (RSD < 3%), accuracy (100.68–102.69%), and robustness.
The UHPLC-DAD/GC-MS method was successfully utilized to analyze volatile components, protocatechuic acid, ferulic acid, and ligustilide, in 13 batches of ZTPs, which is suitable for discrimination and quality assessment of ZTPs.
American Psychological Association (APA)
Liu, Cui-ting& Zhang, Min& Yan, Ping& Liu, Hai-chan& Liu, Xing-yun& Zhan, Ruo-ting. 2016. Qualitative and Quantitative Analysis of Volatile Components of Zhengtian Pills Using Gas Chromatography Mass Spectrometry and Ultra-High Performance Liquid Chromatography. Journal of Analytical Methods in Chemistry،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107262
Modern Language Association (MLA)
Liu, Cui-ting…[et al.]. Qualitative and Quantitative Analysis of Volatile Components of Zhengtian Pills Using Gas Chromatography Mass Spectrometry and Ultra-High Performance Liquid Chromatography. Journal of Analytical Methods in Chemistry No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1107262
American Medical Association (AMA)
Liu, Cui-ting& Zhang, Min& Yan, Ping& Liu, Hai-chan& Liu, Xing-yun& Zhan, Ruo-ting. Qualitative and Quantitative Analysis of Volatile Components of Zhengtian Pills Using Gas Chromatography Mass Spectrometry and Ultra-High Performance Liquid Chromatography. Journal of Analytical Methods in Chemistry. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107262
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107262