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Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology
Joint Authors
Jesus, Mafalda
Martins, Ana P. J.
Gallardo, Eugenia
Silvestre, Samuel
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-28
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Diosgenin, a steroidal sapogenin, occurs abundantly in plants such as Dioscorea alata, Smilax China, and Trigonella foenum graecum.
This bioactive phytochemical not only is used as an important starting material for the preparation of several steroidal drugs in the pharmaceutical industry, but has revealed also high potential and interest in the treatment of various types of disorders such as cancer, hypercholesterolemia, inflammation, and several types of infections.
Due to its pharmacological and industrial importance, several extraction and analytical procedures have been developed and applied over the years to isolate, detect, and quantify diosgenin, not only in its natural sources and pharmaceutical compositions, but also in animal matrices for pharmacodynamic, pharmacokinetic, and toxicological studies.
Within these, HPLC technique coupled to different detectors is the most commonly analytical procedure described for this compound.
However, other alternative methods were also published.
Thus, the present review aims to provide collective information on the most recent pharmacological data on diosgenin and on the most relevant analytical techniques used to isolate, detect, and quantify this compound as well.
American Psychological Association (APA)
Jesus, Mafalda& Martins, Ana P. J.& Gallardo, Eugenia& Silvestre, Samuel. 2016. Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology. Journal of Analytical Methods in Chemistry،Vol. 2016, no. 2016, pp.1-16.
https://search.emarefa.net/detail/BIM-1107312
Modern Language Association (MLA)
Jesus, Mafalda…[et al.]. Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology. Journal of Analytical Methods in Chemistry No. 2016 (2016), pp.1-16.
https://search.emarefa.net/detail/BIM-1107312
American Medical Association (AMA)
Jesus, Mafalda& Martins, Ana P. J.& Gallardo, Eugenia& Silvestre, Samuel. Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology. Journal of Analytical Methods in Chemistry. 2016. Vol. 2016, no. 2016, pp.1-16.
https://search.emarefa.net/detail/BIM-1107312
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107312