The Effect of Salt-Processed Psoralea corylifolia on Generative Organ Targeting
Joint Authors
Yan, Cuiping
Gao, Qianqian
Chen, Zhipeng
Li, Weidong
Zhao, Gen-hua
Xu, Zi-sheng
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-20
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Psoralen and isopsoralen are two isomers and main effective components within Psoralea corylifolia.
In order to investigate the salt-processing effect on tissue distribution characters of psoralen and isopsoralen, a sensitive and accurate ultrahigh pressure liquid chromatographic tandem mass spectrometric (UHPLC-MS/MS) method has been developed and validated for simultaneous determination of the 2 components in rats’ tissues after administration of the extracts that came from either crude or salt-processed Psoralea corylifolia L.
Data displayed that both areas under the curve (AUC) of psoralen and isopsoralen from salt-processed scurfpea fruit group were significantly increased compared with that of the crude herb group, especially in heart (p<0.05), ovary, and testes (p<0.001).
Though the RE and RCmax of psoralen and isopsoralen in all of the investigated organs were over 1.0, generative organs kept the maximum value.
The experiment manifested that salt-processing of scurfpea fruit can increase the distribution of psoralen and isopsoralen to generative organs, heart and spleen, and the distribution of psoralen and isopsoralen to generative organs is significantly higher compared to heart and spleen (p<0.01).
Results indicate that salt-processing of scurfpea fruit can significantly increase the distribution of psoralen and isopsoralen to generative organs.
American Psychological Association (APA)
Zhao, Gen-hua& Yan, Cuiping& Xu, Zi-sheng& Gao, Qianqian& Chen, Zhipeng& Li, Weidong. 2016. The Effect of Salt-Processed Psoralea corylifolia on Generative Organ Targeting. Journal of Analytical Methods in Chemistry،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1107368
Modern Language Association (MLA)
Zhao, Gen-hua…[et al.]. The Effect of Salt-Processed Psoralea corylifolia on Generative Organ Targeting. Journal of Analytical Methods in Chemistry No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1107368
American Medical Association (AMA)
Zhao, Gen-hua& Yan, Cuiping& Xu, Zi-sheng& Gao, Qianqian& Chen, Zhipeng& Li, Weidong. The Effect of Salt-Processed Psoralea corylifolia on Generative Organ Targeting. Journal of Analytical Methods in Chemistry. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1107368
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107368