Urinary Concentrations of Steroids in Bulls under Anabolic Treatment by Revalor-XS® Implant
Joint Authors
Biancotto, Giancarlo
Stella, Roberto
Barrucci, Federica
Lega, Francesca
Angeletti, Roberto
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-20
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Despite the European ban of using anabolics in food-producing animals, growth promoters might still be illegally used in the European Union.
To control the food chain and guarantee consumers’ health, there is a need of highly sensitive analytical methods for the identification of marker residues of such treatments.
In the present study, a group of bulls (n=16) received trenbolone acetate (200 mg) and estradiol (40 mg) by a commercial ear implant during a time range of 71 days, and a second group (n=16) was kept for control.
The aim of the research was to measure the residual urinary concentrations of the administered drugs (β-trenbolone and β-estradiol), their main metabolites (α-trenbolone and α-estradiol), and possible alterations of the urinary profile of other endogenous hormones metabolically related.
The analytical method was based on liquid chromatography-tandem mass spectrometry.
Results showed average urinary concentrations of α-trenbolone and α-estradiol during treatment in the range of (0.81÷2.1) ng mL−1 and (0.96÷4.4) ng mL−1, respectively, whereas β-trenbolone and β-estradiol exhibit urinary concentrations lower than 0.22 ng mL−1 in both cases.
Data obtained from the urinary profiles of endogenous steroids indicate that they could be useful to indirectly detect the ongoing treatment.
American Psychological Association (APA)
Biancotto, Giancarlo& Stella, Roberto& Barrucci, Federica& Lega, Francesca& Angeletti, Roberto. 2016. Urinary Concentrations of Steroids in Bulls under Anabolic Treatment by Revalor-XS® Implant. Journal of Analytical Methods in Chemistry،Vol. 2016, no. 2016, pp.1-16.
https://search.emarefa.net/detail/BIM-1107374
Modern Language Association (MLA)
Biancotto, Giancarlo…[et al.]. Urinary Concentrations of Steroids in Bulls under Anabolic Treatment by Revalor-XS® Implant. Journal of Analytical Methods in Chemistry No. 2016 (2016), pp.1-16.
https://search.emarefa.net/detail/BIM-1107374
American Medical Association (AMA)
Biancotto, Giancarlo& Stella, Roberto& Barrucci, Federica& Lega, Francesca& Angeletti, Roberto. Urinary Concentrations of Steroids in Bulls under Anabolic Treatment by Revalor-XS® Implant. Journal of Analytical Methods in Chemistry. 2016. Vol. 2016, no. 2016, pp.1-16.
https://search.emarefa.net/detail/BIM-1107374
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107374