Synthesis and Antibacterial Activity of Some Derivatives of 2-Methylbenzimidazole Containing 1,3,4-Oxadiazole or 1,2,4-Triazole Heterocycle
Joint Authors
Nguyen Tien, Cong
Tran Thi Cam, Duc
Bui Manh, Ha
Nguyen Dang, Dat
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
5-[(2-Methyl-1H-benzimidazol-1-yl)methyl]-1,3,4-oxadiazole-2-thiol or 5-[(2-methyl-1H-benzimidazol-1-yl)methyl]-4-(4-methylphenyl)-1,2,4-triazol-3-thiol which were prepared starting from 2-methylbenzimidazole in the reaction with appropriate N-aryl-2-chloroacetamides afforded two series of N-aryl-2-{5-[(2-methyl-1H-benzimidazol-1-yl)methyl]-1,3,4-oxadiazol-2-yl}sulfanylacetamides and N-aryl-2-{5-[(2-methyl-1H-benzimidazol-1-yl)methyl]-4-(4-methylphenyl)-4H-1,2,4-triazol-3-ylthio}acetamides, respectively.
The structures of the compounds were elucidated on the basis of IR, MS, 1H-NMR, and 13C-NMR spectral data.
The compounds containing 1,3,4-oxadiazole or 1,2,4-triazole heterocycle also were tested for their antimicrobial activity against bacteria, mold, and yeast.
American Psychological Association (APA)
Nguyen Tien, Cong& Tran Thi Cam, Duc& Bui Manh, Ha& Nguyen Dang, Dat. 2016. Synthesis and Antibacterial Activity of Some Derivatives of 2-Methylbenzimidazole Containing 1,3,4-Oxadiazole or 1,2,4-Triazole Heterocycle. Journal of Chemistry،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1107542
Modern Language Association (MLA)
Nguyen Tien, Cong…[et al.]. Synthesis and Antibacterial Activity of Some Derivatives of 2-Methylbenzimidazole Containing 1,3,4-Oxadiazole or 1,2,4-Triazole Heterocycle. Journal of Chemistry No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1107542
American Medical Association (AMA)
Nguyen Tien, Cong& Tran Thi Cam, Duc& Bui Manh, Ha& Nguyen Dang, Dat. Synthesis and Antibacterial Activity of Some Derivatives of 2-Methylbenzimidazole Containing 1,3,4-Oxadiazole or 1,2,4-Triazole Heterocycle. Journal of Chemistry. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1107542
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107542