Ultrasonic Irradiation: Synthesis, Characterization, and Preliminary Antimicrobial Activity of Novel Series of 4,6-Disubstituted-1,3,5-triazine Containing Hydrazone Derivatives
Joint Authors
Khaled, Jamal M.
Al-Rasheed, Hessa H.
Al Alshaikh, Monirah
El-Faham, Ayman
al-Harbi, Naif O.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Novel series of 4,6-disubstituted-1,3,5-triazines containing hydrazone derivatives were synthesized employing ultrasonic irradiation and conventional heating.
The ultrasonication gave the target products in higher yields and purity in shorter reaction time compared with the conventional method.
IR, NMR ( H 1 and C 13 ), elemental analysis, and LC-MS confirmed the structures of the new products.
The antimicrobial and antifungal activities were evaluated for all the prepared compounds against some selected Gram-positive and Gram-negative bacterial strains.
The results showed that only two compounds 7i (pyridine derivative) and 7k (4-chlorobenzaldehyde derivative) displayed biological activity against some Gram-positive and Gram-negative bacteria, while the rest of the tested compounds did not display any antifungal activity.
American Psychological Association (APA)
Al-Rasheed, Hessa H.& Al Alshaikh, Monirah& Khaled, Jamal M.& al-Harbi, Naif O.& El-Faham, Ayman. 2016. Ultrasonic Irradiation: Synthesis, Characterization, and Preliminary Antimicrobial Activity of Novel Series of 4,6-Disubstituted-1,3,5-triazine Containing Hydrazone Derivatives. Journal of Chemistry،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1107631
Modern Language Association (MLA)
Al-Rasheed, Hessa H.…[et al.]. Ultrasonic Irradiation: Synthesis, Characterization, and Preliminary Antimicrobial Activity of Novel Series of 4,6-Disubstituted-1,3,5-triazine Containing Hydrazone Derivatives. Journal of Chemistry No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1107631
American Medical Association (AMA)
Al-Rasheed, Hessa H.& Al Alshaikh, Monirah& Khaled, Jamal M.& al-Harbi, Naif O.& El-Faham, Ayman. Ultrasonic Irradiation: Synthesis, Characterization, and Preliminary Antimicrobial Activity of Novel Series of 4,6-Disubstituted-1,3,5-triazine Containing Hydrazone Derivatives. Journal of Chemistry. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1107631
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107631