Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic Acid

Abstract EN

Coordination compounds of aspartic acid were synthesized in basic and acidic media, with metal ligand M : L stoichiometric ratio 1 : 2.

The complexes were characterized using infrared, electronic and magnetic susceptibility measurements, and mass spectrometry.

Antimicrobial activity of the compounds was determined against three Gram-positive and three Gram-negative bacteria and one fungus.

The results obtained indicated that the availability of donor atoms used for coordination was a function of the pH of the solution in which the reaction was carried out.

This resulted in varying geometrical structures for the complexes.

The compounds exhibited a broad spectrum of activity and in some cases better activity than the standard.