Spectroscopic, Electrochemical, and In Silico Characterization of Complex Formed between 2-Ferrocenylbenzoic Acid and DNA
Joint Authors
Altaf, Ataf A.
Badshah, Amin
Lal, Bhajan
Khan, Nasir
Ullah, Shafiq
Akbar, Kamran
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
We present the synthesis of 2-ferrocenylbenzoic acid (FcOH) and its electrochemical and spectroscopic characterization.
FcOH was characterized for interaction with DNA using theoretical and experimental methods.
UV-visible spectroscopy and cyclic voltammeter (CV) were used for the experimental account of FcOH-DNA complex.
The experimental results showed that the FcOH interacts by electrostatic mode.
The binding constant ( K b ) and Gibbs free energy ( Δ G ) for the FcOH-DNA complex have been estimated as 5.3 × 104 M−1 and −6.44 kcal/mol, respectively.
The theoretical DNA binding of FcOH was studied with AutoDock molecular docking software.
The docking studies yield good approximation with experimental data and explain the sites of binding.
American Psychological Association (APA)
Altaf, Ataf A.& Lal, Bhajan& Khan, Nasir& Badshah, Amin& Ullah, Shafiq& Akbar, Kamran. 2016. Spectroscopic, Electrochemical, and In Silico Characterization of Complex Formed between 2-Ferrocenylbenzoic Acid and DNA. Journal of Chemistry،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107750
Modern Language Association (MLA)
Altaf, Ataf A.…[et al.]. Spectroscopic, Electrochemical, and In Silico Characterization of Complex Formed between 2-Ferrocenylbenzoic Acid and DNA. Journal of Chemistry No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1107750
American Medical Association (AMA)
Altaf, Ataf A.& Lal, Bhajan& Khan, Nasir& Badshah, Amin& Ullah, Shafiq& Akbar, Kamran. Spectroscopic, Electrochemical, and In Silico Characterization of Complex Formed between 2-Ferrocenylbenzoic Acid and DNA. Journal of Chemistry. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107750
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107750