An Overview of Murine High Fat Diet as a Model for Type 2 Diabetes Mellitus
Author
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-31
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Type 2 diabetes mellitus (T2DM) is a worldwide epidemic, which by all predictions will only increase.
To help in combating the devastating array of phenotypes associated with T2DM a highly reproducible and human disease-similar mouse model is required for researchers.
The current options are genetic manipulations to cause T2DM symptoms or diet induced obesity and T2DM symptoms.
These methods to model human T2DM have their benefits and their detractions.
As far as modeling the majority of T2DM cases, HFD establishes the proper etiological, pathological, and treatment options.
A limitation of HFD is that it requires months of feeding to achieve the full spectrum of T2DM symptoms and no standard protocol has been established.
This paper will attempt to rectify the last limitation and argue for a standard group of HFD protocols and standard analysis procedures.
American Psychological Association (APA)
Heydemann, Ahlke. 2016. An Overview of Murine High Fat Diet as a Model for Type 2 Diabetes Mellitus. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1108038
Modern Language Association (MLA)
Heydemann, Ahlke. An Overview of Murine High Fat Diet as a Model for Type 2 Diabetes Mellitus. Journal of Diabetes Research No. 2016 (2016), pp.1-14.
https://search.emarefa.net/detail/BIM-1108038
American Medical Association (AMA)
Heydemann, Ahlke. An Overview of Murine High Fat Diet as a Model for Type 2 Diabetes Mellitus. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1108038
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108038