The Association of Retinopathy and Plasma Glucose and HbA1c: A Validation of Diabetes Diagnostic Criteria in a Chinese Population
Joint Authors
Cai, Xiaoling
Ji, Linong
Zhang, Rui
Li, Yufeng
Zhang, Simin
Zhou, Xianghai
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-11
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Aims.
This study aimed to evaluate the associations of diabetic retinopathy (DR) with fasting plasma glucose (FPG), 2-hour postload plasma glucose (2hPG), and glycated hemoglobin A1c (HbA1c) in a Chinese population.
Materials and Methods.
A total of 3124 participants, identified from a population-based survey in Pinggu district, were examined by retinal photography (45°).
DR was classified according to the Early Treatment Diabetic Retinopathy Study scale.
FPG, 2hPG, and HbA1c were tested and categorized by deciles, with the prevalence of DR calculated in each decile.
Results.
The prevalence of DR increased sharply in the 10th deciles, when FPG exceeded 7.03 mmol/L and HbA1c exceeded 6.4%.
Analysis of the receiver operating characteristic curves showed that the optimal cutoffs for detecting DR were 6.52 mmol/L and 5.9% for FPG and HbA1c, respectively.
The World Health Organization (WHO) criteria for diagnosing diabetes showed high specificity (90.5–99.5%) and low sensitivity (35.3–65.0%).
Further, 6 individuals with retinopathy had normal plasma glucose; however, their characteristics did not differ from those without retinopathy.
Conclusions.
Thresholds of FPG and HbA1c for detecting DR were observed, and the WHO criteria of diagnosing diabetes were shown to have high specificity and low sensitivity in this population.
American Psychological Association (APA)
Zhang, Rui& Li, Yufeng& Zhang, Simin& Cai, Xiaoling& Zhou, Xianghai& Ji, Linong. 2016. The Association of Retinopathy and Plasma Glucose and HbA1c: A Validation of Diabetes Diagnostic Criteria in a Chinese Population. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108091
Modern Language Association (MLA)
Zhang, Rui…[et al.]. The Association of Retinopathy and Plasma Glucose and HbA1c: A Validation of Diabetes Diagnostic Criteria in a Chinese Population. Journal of Diabetes Research No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1108091
American Medical Association (AMA)
Zhang, Rui& Li, Yufeng& Zhang, Simin& Cai, Xiaoling& Zhou, Xianghai& Ji, Linong. The Association of Retinopathy and Plasma Glucose and HbA1c: A Validation of Diabetes Diagnostic Criteria in a Chinese Population. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108091
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108091