![](/images/graphics-bg.png)
The Adenosinergic System in Diabetic Retinopathy
Joint Authors
Santiago, Ana R.
Santos, Paulo F.
Ambrósio, António F.
Vindeirinho, J.
Cavadas, C.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The neurodegenerative and inflammatory environment that is prevalent in the diabetic eye is a key player in the development and progression of diabetic retinopathy.
The adenosinergic system is widely regarded as a significant modulator of neurotransmission and the inflammatory response, through the actions of the four types of adenosine receptors (A1R, A2AR, A2BR, and A3R), and thus could be revealed as a potential player in the events unfolding in the early stages of diabetic retinopathy.
Herein, we review the studies that explore the impact of diabetic conditions on the retinal adenosinergic system, as well as the role of the said system in ameliorating or exacerbating those conditions.
The experimental results described suggest that this system is heavily affected by diabetic conditions and that the modulation of its components could reveal potential therapeutic targets for the treatment of diabetic retinopathy, particularly in the early stages of the disease.
American Psychological Association (APA)
Vindeirinho, J.& Santiago, Ana R.& Cavadas, C.& Ambrósio, António F.& Santos, Paulo F.. 2016. The Adenosinergic System in Diabetic Retinopathy. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1108106
Modern Language Association (MLA)
Vindeirinho, J.…[et al.]. The Adenosinergic System in Diabetic Retinopathy. Journal of Diabetes Research No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1108106
American Medical Association (AMA)
Vindeirinho, J.& Santiago, Ana R.& Cavadas, C.& Ambrósio, António F.& Santos, Paulo F.. The Adenosinergic System in Diabetic Retinopathy. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1108106
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108106