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Impact of Real-Time Continuous Glucose Monitoring Use on Glucose Variability and Endothelial Function in Adolescents with Type 1 Diabetes: New Technology—New Possibility to Decrease Cardiovascular Risk?
Joint Authors
Jamiołkowska, Milena
Jamiołkowska, Izabela
Bossowski, Artur
Łuczyński, Włodzimierz
Tołwińska, Joanna
Głowińska-Olszewska, Barbara
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Children with type 1 diabetes (T1DM) are the high-risk group of accelerated atherosclerosis.
Real-time continuous glucose monitoring (RT-CGM) provides possibilities for the detection of glycaemic variability, newly recognized cardiovascular risk factor.
The aim of the study was to assess the usefulness of RT-CGM as an educational tool to find and reduce glycaemic variability in order to improve endothelial function in T1DM adolescents.
Forty patients aged 14.6 years were recruited.
The study was based on one-month CGM sensors use.
Parameters of glycaemic variability were analyzed during first and last sensor use, together with brachial artery flow-mediated dilatation (FMD) to assess endothelial function.
In the whole group, FMD improvement was found (10.9% to 16.6%, p<0.005), together with decrease in all studied glycaemic variability parameters.
In patients with HbA1c improvement compared to the group without HbA1c improvement, we found greater increase of FMD (12% to 19%, p<0.005 versus 8.2% to 11.3%, p=0.080) and greater improvement of glucose variability.
RT-CGM can be considered as an additional tool that offers T1DM adolescents the quick reaction to decrease glycaemic variability in short time observation.
Whether such approach might influence improvement in endothelial function and reduction of the risk of future cardiovascular disease remains to be elucidated.
American Psychological Association (APA)
Jamiołkowska, Milena& Jamiołkowska, Izabela& Łuczyński, Włodzimierz& Tołwińska, Joanna& Bossowski, Artur& Głowińska-Olszewska, Barbara. 2015. Impact of Real-Time Continuous Glucose Monitoring Use on Glucose Variability and Endothelial Function in Adolescents with Type 1 Diabetes: New Technology—New Possibility to Decrease Cardiovascular Risk?. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1108113
Modern Language Association (MLA)
Jamiołkowska, Milena…[et al.]. Impact of Real-Time Continuous Glucose Monitoring Use on Glucose Variability and Endothelial Function in Adolescents with Type 1 Diabetes: New Technology—New Possibility to Decrease Cardiovascular Risk?. Journal of Diabetes Research No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1108113
American Medical Association (AMA)
Jamiołkowska, Milena& Jamiołkowska, Izabela& Łuczyński, Włodzimierz& Tołwińska, Joanna& Bossowski, Artur& Głowińska-Olszewska, Barbara. Impact of Real-Time Continuous Glucose Monitoring Use on Glucose Variability and Endothelial Function in Adolescents with Type 1 Diabetes: New Technology—New Possibility to Decrease Cardiovascular Risk?. Journal of Diabetes Research. 2015. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1108113
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108113