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Diabetic Microangiopathy Is an Independent Predictor of Incident Diabetic Foot Ulcer
Joint Authors
Oikawa, Yoichi
Shimada, A.
Matsuoka, K.
Tomita, Masuomi
Okisugi, Mari
Atsumi, Yoshihito
Katsuki, Takeshi
Kabeya, Yusuke
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
To determine the diabetic foot ulcer incidence and examine its association with microangiopathy complications, including diabetic retinopathy (DR) and albuminuria (Alb), in type 2 diabetes patients.
Methods.
This was a retrospective cohort study of 1,305 patients with type 2 diabetes who were assigned to the following groups: Category 1, normoalbuminuria without DR (n=712); Category 2, Alb without DR (n=195); Category 3, normoalbuminuria with DR (n=185); and Category 4, Alb with DR (n=213).
Cox proportional hazard models were used to compare the risks of developing diabetic foot ulcers across the categories.
Results.
During 14,249 person-years of follow-up, 50 subjects developed diabetic foot ulcers, with incidence rates of 1.6/1,000, 1.5/1,000, 3.4/1,000, and 12.5/1,000 person-years in Categories 1, 2, 3, and 4, respectively.
After adjusting for the presence of diabetic neuropathy and macroangiopathy, the hazard ratios and 95% confidence intervals (CIs) for the risk of diabetic foot ulcer development were 0.66 (95% CI, 0.18–2.36), 1.72 (95% CI, 0.67–4.42), and 3.17 (95% CI, 1.52–6.61) in Categories 2, 3, and 4, respectively, compared with Category 1.
Conclusion.
The presence of DR and Alb significantly increases the risk of diabetic foot ulcer development.
American Psychological Association (APA)
Tomita, Masuomi& Kabeya, Yusuke& Okisugi, Mari& Katsuki, Takeshi& Oikawa, Yoichi& Atsumi, Yoshihito…[et al.]. 2016. Diabetic Microangiopathy Is an Independent Predictor of Incident Diabetic Foot Ulcer. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1108178
Modern Language Association (MLA)
Tomita, Masuomi…[et al.]. Diabetic Microangiopathy Is an Independent Predictor of Incident Diabetic Foot Ulcer. Journal of Diabetes Research No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1108178
American Medical Association (AMA)
Tomita, Masuomi& Kabeya, Yusuke& Okisugi, Mari& Katsuki, Takeshi& Oikawa, Yoichi& Atsumi, Yoshihito…[et al.]. Diabetic Microangiopathy Is an Independent Predictor of Incident Diabetic Foot Ulcer. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1108178
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108178