The Relation between Serum Uric Acid and HbA1c Is Dependent upon Hyperinsulinemia in Patients with Newly Diagnosed Type 2 Diabetes Mellitus
Joint Authors
Cui, Yuliang
Bu, Hemei
Ma, Xianghua
Zhao, Sha
Li, Xiaona
Lu, Shan
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-14
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
The aim of our study was to explore the dependent condition of the relationship between uric acid and blood glucose in type 2 diabetes.
Research Design and Methods.
We measured the HbA1c, serum uric acid, creatinine, lipids profiles, and so forth of 605 newly diagnosed type 2 diabetes patients, and oral glucose tolerance tests (OGTTs) were performed on each patient.
The population was divided into high and low insulin groups.
Multiple linear regression analyses were conducted to assess the relationship between uric acid and HbA1c.
Results.
Serum uric acid and HbA1c levels were low in newly diagnosed type 2 diabetes patients.
However, we found no significant relationship between uric acid and HbA1c by regression analysis after adjusting total insulin.
The concentration of uric acid was inversely correlated with HbA1c in the high insulin group, regardless of patient sex.
However, no associations were found in low insulin group.
Conclusions.
The negative correlation between uric acid and HbA1c is conditional in newly diagnosed type 2 diabetes patients and is related to hyperinsulinemia.
Therefore, uric acid is likely only useful as a biomarker of blood glucose in patients exhibiting hyperinsulinemia.
American Psychological Association (APA)
Cui, Yuliang& Bu, Hemei& Ma, Xianghua& Zhao, Sha& Li, Xiaona& Lu, Shan. 2016. The Relation between Serum Uric Acid and HbA1c Is Dependent upon Hyperinsulinemia in Patients with Newly Diagnosed Type 2 Diabetes Mellitus. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1108227
Modern Language Association (MLA)
Cui, Yuliang…[et al.]. The Relation between Serum Uric Acid and HbA1c Is Dependent upon Hyperinsulinemia in Patients with Newly Diagnosed Type 2 Diabetes Mellitus. Journal of Diabetes Research No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1108227
American Medical Association (AMA)
Cui, Yuliang& Bu, Hemei& Ma, Xianghua& Zhao, Sha& Li, Xiaona& Lu, Shan. The Relation between Serum Uric Acid and HbA1c Is Dependent upon Hyperinsulinemia in Patients with Newly Diagnosed Type 2 Diabetes Mellitus. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1108227
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108227