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Insulin Resistance and Obesity Affect Lipid Profile in the Salivary Glands
Joint Authors
Łukaszuk, Bartłomiej
Knaś, M.
Maciejczyk, M.
Matczuk, J.
Zalewska, A.
Garbowska, Marta
Ziembicka, Dominika M.
Waszkiel, Danuta
Kurek, Krzysztof
Chabowski, Adrian
Żendzian-Piotrowska, Małgorzata
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
In today’s world wrong nutritional habits together with a low level of physical activity have given rise to the development of obesity and its comorbidity, insulin resistance.
More specifically, many researches indicate that lipids are vitally involved in the onset of a peripheral tissue (e.g., skeletal muscle, heart, and liver) insulin resistance.
Moreover, it seems that diabetes can also induce changes in respect of lipid composition of both the salivary glands and saliva.
However, judging by the number of research articles, the salivary glands lipid profile still has not been sufficiently explored.
In the current study we aim to assess the changes in the main lipid fractions, namely, triacylglycerols, phospholipids, free fatty acids, and diacylglycerols, in the parotid and the submandibular salivary glands of rats exposed to a 5-week high fat diet regimen.
We observed that the high caloric fat diet caused a significant change in the salivary glands lipid composition, especially with respect to PH and TG, but not DAG or FFAs, classes.
The observed reduction in PH concentration is an interesting phenomenon frequently signifying the atrophy and malfunctions in the saliva secreting organs.
On the other hand, the increased accumulation of TG in the glands may be an important clinical manifestation of metabolic syndrome and type 2 diabetes mellitus.
American Psychological Association (APA)
Matczuk, J.& Zalewska, A.& Łukaszuk, Bartłomiej& Knaś, M.& Maciejczyk, M.& Garbowska, Marta…[et al.]. 2016. Insulin Resistance and Obesity Affect Lipid Profile in the Salivary Glands. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1108267
Modern Language Association (MLA)
Matczuk, J.…[et al.]. Insulin Resistance and Obesity Affect Lipid Profile in the Salivary Glands. Journal of Diabetes Research No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1108267
American Medical Association (AMA)
Matczuk, J.& Zalewska, A.& Łukaszuk, Bartłomiej& Knaś, M.& Maciejczyk, M.& Garbowska, Marta…[et al.]. Insulin Resistance and Obesity Affect Lipid Profile in the Salivary Glands. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1108267
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108267