High Serum Adipocyte Fatty Acid Binding Protein Is Associated with Metabolic Syndrome in Patients with Type 2 Diabetes
Joint Authors
Li, Jer-Chuan
Wu, Du-An
Hou, Jia-Sian
Subeq, Yi-Maun
Chen, Hsin-Dean
Hsu, Bang-Gee
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Adipocyte fatty acid binding protein (A-FABP) is a key mediator of obesity-related metabolic syndrome (MetS).
The aim of this study was to evaluate the relationship between A-FABP concentration and MetS in type 2 diabetes mellitus (DM) patients.
Fasting blood samples were obtained from 165 type 2 DM volunteers.
MetS and its components were defined using diagnostic criteria from the International Diabetes Federation.
Among 165 DM patients, 113 patients (68.5%) had MetS.
Diabetic persons who had MetS had significantly higher A-FABP levels (P<0.001) than those without MetS.
Female DM persons had higher A-FABP level than man (P<0.001).
No statistically significant differences in A-FABP levels were found in use of statin, fibrate, or antidiabetic drugs.
Multivariate forward stepwise linear regression analysis revealed that body fat mass (P<0.001), logarithmically transformed creatinine (log-creatinine; P<0.001), female DM patients (P<0.001), and logarithmically transformed high sensitive C-reactive protein (log-hs-CRP; P=0.013) were positively correlated, while albumin (P=0.004) and glomerular filtration rate (GFR; P=0.043) were negatively correlated with serum A-FABP levels in type 2 DM patients.
In this study, higher serum A-FABP level was positively associated with MetS in type 2 DM patients.
American Psychological Association (APA)
Li, Jer-Chuan& Wu, Du-An& Hou, Jia-Sian& Subeq, Yi-Maun& Chen, Hsin-Dean& Hsu, Bang-Gee. 2016. High Serum Adipocyte Fatty Acid Binding Protein Is Associated with Metabolic Syndrome in Patients with Type 2 Diabetes. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108280
Modern Language Association (MLA)
Li, Jer-Chuan…[et al.]. High Serum Adipocyte Fatty Acid Binding Protein Is Associated with Metabolic Syndrome in Patients with Type 2 Diabetes. Journal of Diabetes Research No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1108280
American Medical Association (AMA)
Li, Jer-Chuan& Wu, Du-An& Hou, Jia-Sian& Subeq, Yi-Maun& Chen, Hsin-Dean& Hsu, Bang-Gee. High Serum Adipocyte Fatty Acid Binding Protein Is Associated with Metabolic Syndrome in Patients with Type 2 Diabetes. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108280
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108280