Antidiabetic and Antioxidant Impacts of Desert Date (Balanites aegyptiaca) and Parsley (Petroselinum sativum) Aqueous Extracts: Lessons from Experimental Rats
Joint Authors
Aqeely, Hussein
Abou Khalil, Nasser S.
Wasfy, Salwa I. A.
El Mileegy, Ibtisam M. H.
Hamed, Mohamed Y.
Abou-Elhamd, Alaa Sayed
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-25
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Medicinal plants are effective in controlling plasma glucose level with minimal side effects and are commonly used in developing countries as an alternative therapy for the treatment of type 1 diabetes mellitus.
The aim of this study is to evaluate the potential antidiabetic and antioxidant impacts of Balanites aegyptiaca and Petroselinum sativum extracts on streptozotocin-induced diabetic and normal rats.
The influences of these extracts on body weight, plasma glucose, insulin, total antioxidant capacity (TAC), malondialdehyde (MDA) levels, and liver-pyruvate kinase (L-PK) levels were assessed.
Furthermore, the weight and histomorphological changes of the pancreas were studied in the different experimental groups.
The herbal preparations significantly reduced the mean plasma glucose and MDA levels and significantly increased the mean plasma insulin, L-PK, and TAC levels in the treated diabetic groups compared to the diabetic control group.
An obvious increase in the weight of the pancreas and the size of the islets of Langerhans and improvement in the histoarchitecture were evident in the treated groups compared to untreated ones.
In conclusion, the present study provides a scientific evidence for the traditional use of these extracts as antidiabetic and antioxidant agents in type 1 diabetes mellitus.
American Psychological Association (APA)
Abou Khalil, Nasser S.& Abou-Elhamd, Alaa Sayed& Wasfy, Salwa I. A.& El Mileegy, Ibtisam M. H.& Hamed, Mohamed Y.& Aqeely, Hussein. 2016. Antidiabetic and Antioxidant Impacts of Desert Date (Balanites aegyptiaca) and Parsley (Petroselinum sativum) Aqueous Extracts: Lessons from Experimental Rats. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1108282
Modern Language Association (MLA)
Abou Khalil, Nasser S.…[et al.]. Antidiabetic and Antioxidant Impacts of Desert Date (Balanites aegyptiaca) and Parsley (Petroselinum sativum) Aqueous Extracts: Lessons from Experimental Rats. Journal of Diabetes Research No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1108282
American Medical Association (AMA)
Abou Khalil, Nasser S.& Abou-Elhamd, Alaa Sayed& Wasfy, Salwa I. A.& El Mileegy, Ibtisam M. H.& Hamed, Mohamed Y.& Aqeely, Hussein. Antidiabetic and Antioxidant Impacts of Desert Date (Balanites aegyptiaca) and Parsley (Petroselinum sativum) Aqueous Extracts: Lessons from Experimental Rats. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1108282
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108282